Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 6/20 | 0.58 |
| ▸ | PRKD3 | O94806 | 3/20 | 0.54 |
| ▸ | PRKCG | P05129 | 3/20 | 0.54 |
| ▸ | PRKCB | P05771 | 3/20 | 0.54 |
| ▸ | PRKCA | P17252 | 3/20 | 0.54 |
| ▸ | PRKCH | P24723 | 3/20 | 0.54 |
| ▸ | PRKCI | P41743 | 3/20 | 0.54 |
| ▸ | PRKCE | Q02156 | 3/20 | 0.54 |
| ▸ | PRKCQ | Q04759 | 3/20 | 0.54 |
| ▸ | PRKCZ | Q05513 | 3/20 | 0.54 |
| ▸ | PRKCD | Q05655 | 3/20 | 0.54 |
| ▸ | PRKD1 | Q15139 | 3/20 | 0.54 |
| ▸ | LPAR3 | Q9UBY5 | 10/20 | 0.51 |
| ▸ | LPAR1 | Q92633 | 9/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | LPAR5 | Q9H1C0 | 4/20 | 0.46 |
| ▸ | LPAR2 | Q9HBW0 | 4/20 | 0.46 |
| ▸ | LPAR6 | P43657 | 3/20 | 0.46 |
| ▸ | LPAR4 | Q99677 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11087950 | 1.00 | ENPP2 (0.58) | ENPP2PRKD3PRKCGPRKCBPRKCA | |
| SCHEMBL8677600 | 1.00 | ENPP2 (0.58) | ENPP2PRKD3PRKCGPRKCBPRKCA | |
| SCHEMBL11085679 | 0.93 | LPAR3 (0.59) | ENPP2PRKD3PRKCGPRKCBPRKCA | |
| SCHEMBL11087665 | 0.93 | LPAR3 (0.59) | ENPP2PRKD3PRKCGPRKCBPRKCA | |
| SCHEMBL11089242 | 0.92 | ENPP2 (0.63) | ENPP2LPAR3LPAR1LPAR5LPAR2 | |
| SCHEMBL11090082 | 0.91 | ENPP2 (0.50) | ENPP2PRKD3PRKCGPRKCBPRKCA | |
| SCHEMBL11081529 | 0.91 | LPAR3 (0.59) | ENPP2PRKD3PRKCGPRKCBPRKCA | |
| SCHEMBL11084346 | 0.89 | S1PR1 (0.57) | ENPP2PRKD3PRKCGPRKCBPRKCA | |
| SCHEMBL11088836 | 0.89 | ENPP2 (0.60) | ENPP2LPAR3LPAR1LPAR5LPAR2 | |
| SCHEMBL11084243 | 0.89 | ENPP2 (0.48) | ENPP2PRKD3PRKCGPRKCBPRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4444766-A | ANTITUMOR | BOEHRINGER MANNHEIM GMBH (DE) | 1984-04-24 | — | — | US | claimed |
| US-4444766-A | ANTITUMOR | BOEHRINGER MANNHEIM GMBH (DE) | 1984-04-24 | — | — | US | disclosed |