Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 13/20 | 0.57 |
| ▸ | S1PR4 | O95977 | 12/20 | 0.57 |
| ▸ | S1PR3 | Q99500 | 10/20 | 0.57 |
| ▸ | S1PR2 | O95136 | 3/20 | 0.57 |
| ▸ | S1PR5 | Q9H228 | 11/20 | 0.51 |
| ▸ | ENPP2 | Q13822 | 5/20 | 0.48 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.44 |
| ▸ | PRKCG | P05129 | 2/20 | 0.44 |
| ▸ | PRKCB | P05771 | 2/20 | 0.44 |
| ▸ | PRKCA | P17252 | 2/20 | 0.44 |
| ▸ | PRKCH | P24723 | 2/20 | 0.44 |
| ▸ | PRKCI | P41743 | 2/20 | 0.44 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.44 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.44 |
| ▸ | PRKCZ | Q05513 | 2/20 | 0.44 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.44 |
| ▸ | PRKD1 | Q15139 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11087950 | 0.89 | ENPP2 (0.58) | ENPP2PRKD3PRKCGPRKCBPRKCA | |
| SCHEMBL8677600 | 0.89 | ENPP2 (0.58) | ENPP2PRKD3PRKCGPRKCBPRKCA | |
| SCHEMBL11078070 | 0.89 | ENPP2 (0.58) | ENPP2PRKD3PRKCGPRKCBPRKCA | |
| Phosphoric Acid SCHEMBL11084345 | 0.86 | ENPP2 (0.48) | S1PR1S1PR4S1PR3S1PR2S1PR5 | |
| SCHEMBL11087665 | 0.83 | LPAR3 (0.59) | ENPP2PRKD3PRKCGPRKCBPRKCA | |
| SCHEMBL11085679 | 0.83 | LPAR3 (0.59) | ENPP2PRKD3PRKCGPRKCBPRKCA | |
| SCHEMBL11089242 | 0.82 | ENPP2 (0.63) | S1PR1S1PR4S1PR3S1PR2S1PR5 | |
| SCHEMBL11090320 | 0.81 | ENPP2 (0.44) | S1PR1S1PR4S1PR3S1PR2ENPP2 | |
| SCHEMBL11088836 | 0.81 | ENPP2 (0.60) | S1PR1S1PR4S1PR3S1PR2S1PR5 | |
| SCHEMBL11090082 | 0.81 | ENPP2 (0.50) | ENPP2PRKD3PRKCGPRKCBPRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4444766-A | ANTITUMOR | BOEHRINGER MANNHEIM GMBH (DE) | 1984-04-24 | — | — | US | disclosed |