SCHEMBL11078073

SCHEMBL11078073

Cc1ccc(S(=O)(=O)Nc2cc(Br)c(N)c3c2C(=O)c2ccccc2C3=O)cc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDK2 P24941 1/20 0.71
PGAM1 P18669 1/20 0.58
MAPT P10636 5/20 0.56
ALDH1A1 P00352 4/20 0.56
LMNA P02545 3/20 0.56
POLB P06746 3/20 0.56
L3MBTL1 Q9Y468 3/20 0.56
CYP2C9 P11712 2/20 0.56
CYP2C19 P33261 2/20 0.56
USP2 O75604 1/20 0.56
NOD2 Q9HC29 1/20 0.56
P2RY4 P51582 6/20 0.53
P2RY2 P41231 5/20 0.53
CA2 P00918 2/20 0.51
CA9 Q16790 2/20 0.51
CA12 O43570 1/20 0.51
MCOLN3 Q8TDD5 1/20 0.51
PTPRC P08575 1/20 0.51
MEN1 O00255 4/20 0.49
KMT2A Q03164 4/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10778264 0.91 CDK2 (0.57) CDK2PGAM1MAPTALDH1A1LMNA
SCHEMBL10487975 0.91 CDK2 (0.57) CDK2PGAM1MAPTALDH1A1LMNA
SCHEMBL10488023 0.91 CDK2 (0.59) CDK2PGAM1MAPTALDH1A1LMNA
SCHEMBL10488101 0.91 CDK2 (0.59) CDK2PGAM1MAPTALDH1A1LMNA
SCHEMBL11599550 0.90 CDK2 (0.56) CDK2PGAM1MAPTALDH1A1LMNA
SCHEMBL10488020 0.90 CDK2 (0.58) CDK2PGAM1MAPTALDH1A1LMNA
SCHEMBL10900097 0.88 CDK2 (0.56) CDK2PGAM1MAPTALDH1A1LMNA
SCHEMBL10777776 0.87 CDK2 (0.55) CDK2PGAM1MAPTLMNAP2RY4
SCHEMBL11782999 0.85 CDK2 (0.71) CDK2PGAM1MAPTALDH1A1LMNA
SCHEMBL28194417 0.85 CDK2 (0.71) CDK2PGAM1MAPTALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4288362-A Monoazo pigments containing a quinazo linonylacetoacetanilide coupling component BAYER AKTIENGESELLSCHAFT (DE) 1981-09-08 US claimed
US-10385215-B2 Polymerizable dichroic dyes ROLIC AG (CH) 2019-08-20 US disclosed
US-20170058126-A1 POLYMERIZABLE DICHROIC DYES ROLIC AG (CH) 2017-03-02 US disclosed
US-20170058126-A1 POLYMERIZABLE DICHROIC DYES ROLIC AG (CH) 2017-03-02 US disclosed
EP-0008627-B1 QUINAZOLINE DERIVATIVES, AZO DYES DERIVED FROM THE QUINAZOLINES AND THEIR USE AS PIGMENTS BAYER AG (DE) 1984-10-03 EP disclosed
US-4389215-A Anthraquinone-azomethine compounds, processes for their preparation and processes for dyeing synthetic fibre materials and for pigmenting organic macromolecular substances BAYER AKTIENGESELLSCHAFT (DE) 1983-06-21 US disclosed
EP-0018538-B1 ANTHRAQUINONE DERIVATIVES, PROCESS FOR THEIR PREPARATION, PROCESS FOR THE PIGMENTATION OF ORGANIC MACROMOLECULAR MATERIALS AND PIGMENTED ORGANIC MACROMOLECULAR MATERIAL BAYER AG (DE) 1983-05-11 EP disclosed
EP-0023648-B1 ANTHRAQUINONE-AZOMETHINE COMPOUNDS, PROCESS FOR THEIR PREPARATION; PROCESS FOR DYEING SYNTHETIC FIBRE MATERIALS AS WELL AS FOR PIGMENTING ORGANIC MACROMOLECULAR MATERIALS BAYER AG (DE) 1982-06-23 EP disclosed
US-4323671-A Anthraquinone derivatives, processes for their preparation, processes for pigmenting organic macromolecular substances, and pigmented organic macromolecular material BAYER AKTIENGESELLSCHAFT (DE) 1982-04-06 US disclosed
US-4323670-A Anthraquinone-azomethine compounds, processes for their preparation and processes for pigmenting organic macromolecular substances BAYER AKTIENGESELLSCHAFT (DE) 1982-04-06 US disclosed
US-4246401-A Axomethine pigments BAYER AKTIENGESELLSCHAFT (DE) 1981-01-20 US disclosed
EP-0018538-A2 Anthraquinone derivatives, process for their preparation, process for the pigmentation of organic macromolecular materials and pigmented organic macromolecular material BAYER AG (DE) 1980-11-12 EP disclosed
US-4225489-A Heterocyclic azo dyes and pigments containing 4-quinazolinone moieties BAYER AKTIENGESELLSCHAFT (DE) 1980-09-30 US disclosed
EP-0008627-A2 Quinazoline derivatives, azo dyes derived from the quinazolines and their use as pigments BAYER AG (DE) 1980-03-19 EP disclosed
EP-0008063-A1 Azomethine derivatives of anthraquinones, methods for their preparation, their use in the pigmentation of organic macromolecular compounds and the materials thus obtained BAYER AG (DE) 1980-02-20 EP disclosed
US-RE29577-E Anthraquinone dyestuffs BAYER AKTIENGESELLSCHAFT (DT) 1978-03-14 US disclosed
US-4040812-A Herbicidal carbonates and thiocarbonates of thiadiazolyl-2(1H)-pyrimidinones VELSICOL CHEMICAL CORPORATION (US) 1977-08-09 US disclosed
US-3963763-A Anthraquinone dyestuffs BAYER AKTIENGESELLSCHAFT (DT) 1976-06-15 US disclosed
US-3959315-A SULFONAMIDO BAYER AKTIENGESELLSCHAFT (DT) 1976-05-25 US disclosed
US-3957822-A POLYAMIDES BAYER AKTIENGESELLSCHAFT (DT) 1976-05-18 US disclosed