SCHEMBL11599550

SCHEMBL11599550

Nc1c(Br)cc(NS(=O)(=O)c2ccccc2)c2c1C(=O)c1ccccc1C2=O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDK2 P24941 3/20 0.56
PGAM1 P18669 4/20 0.54
MEN1 O00255 3/20 0.47
LMNA P02545 3/20 0.47
MAPT P10636 3/20 0.47
KMT2A Q03164 3/20 0.47
ALDH1A1 P00352 2/20 0.47
KDM4E B2RXH2 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
FTO Q9C0B1 1/20 0.47
P2RY4 P51582 5/20 0.46
P2RY12 Q9H244 4/20 0.46
P2RY2 P41231 3/20 0.46
P2RY1 P47900 2/20 0.46
P2RY6 Q15077 2/20 0.46
NAT1 P18440 3/20 0.46
CYP1A2 P05177 1/20 0.46
CYP3A4 P08684 1/20 0.46
CYP2C9 P11712 1/20 0.46
HPGD P15428 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11078073 0.90 CDK2 (0.71) CDK2PGAM1MEN1LMNAMAPT
SCHEMBL11600772 0.84 PGAM1 (0.51) CDK2PGAM1MEN1MAPTKMT2A
SCHEMBL11601303 0.82 CDK2 (0.52) CDK2MEN1MAPTKMT2AALDH1A1
SCHEMBL11599555 0.81 PGAM1 (0.62) CDK2PGAM1MEN1LMNAMAPT
SCHEMBL11612508 0.81 GNG2 (0.64) CDK2PGAM1MEN1KMT2AALDH1A1
SCHEMBL10488101 0.80 CDK2 (0.59) CDK2PGAM1MEN1LMNAMAPT
SCHEMBL10488023 0.80 CDK2 (0.59) CDK2PGAM1MEN1LMNAMAPT
SCHEMBL7534353 0.80 CDK2 (0.84) CDK2MEN1KMT2AP2RY4P2RY12
SCHEMBL7534351 0.80 GNG2 (0.63) CDK2PGAM1MEN1KMT2AALDH1A1
SCHEMBL7566865 0.80 CDK2 (0.56) CDK2PGAM1MEN1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE29577-E Anthraquinone dyestuffs BAYER AKTIENGESELLSCHAFT (DT) 1978-03-14 US disclosed
US-3963763-A Anthraquinone dyestuffs BAYER AKTIENGESELLSCHAFT (DT) 1976-06-15 US disclosed