Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | TEK | Q02763 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | DHFR | P00374 | 1/20 | 0.38 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11086416 | 0.87 | PARP1 (0.51) | PARP1TEKLMNATSHRMAPT | |
| SCHEMBL11078271 | 0.86 | PARP1 (0.50) | PARP1LMNAMAPTDHFRSHMT2 | |
| SCHEMBL11081129 | 0.84 | PARP1 (0.48) | PARP1MAPTDHFRSHMT2ADORA3 | |
| SCHEMBL11080835 | 0.82 | PARP1 (0.46) | PARP1LMNATSHRHSD17B10DHFR | |
| SCHEMBL11086406 | 0.82 | PARP1 (0.46) | PARP1LMNATSHRMAPTHSD17B10 | |
| SCHEMBL11080557 | 0.82 | PARP1 (0.46) | PARP1TSHRMAPTDHFRSHMT2 | |
| SCHEMBL11076059 | 0.81 | TLR7 (0.48) | PARP1LMNATSHRMAPTHSD17B10 | |
| SCHEMBL11083854 | 0.81 | PARP1 (0.46) | PARP1DHFRSHMT2ADORA3ADORA2A | |
| Hydrochloric Acid SCHEMBL11077145 | 0.81 | PARP1 (0.52) | PARP1LMNATSHRMAPTHSD17B10 | |
| SCHEMBL11073129 | 0.81 | PARP1 (0.55) | PARP1LMNATSHRMAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4435417-A | ANTIINFLAMMATORY AGENTS | GRUPPO LEPETIT S.P.A. (IT) | 1984-03-06 | — | — | US | disclosed |
| EP-0012866-A1 | New 3H-naphtho(1,2-d)imidazoles, processes for preparing them, compounds for use as antiinflammatory and antimicrobial agents and compositions for that use containing them | GRUPPO LEPETIT S.P.A. (IT) | 1980-07-09 | — | — | EP | disclosed |