Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.48 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.44 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.44 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11086416 | 0.91 | PARP1 (0.51) | PARP1KDM4ESMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL11076859 | 0.85 | APP (0.44) | PARP1KDM4ESMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL11078271 | 0.84 | PARP1 (0.50) | PARP1KDM4EALDH1A1HPGDRAB9A | |
| SCHEMBL11073129 | 0.84 | PARP1 (0.55) | TLR7PARP1KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL11290186 | 0.84 | KMT2A (0.42) | KDM4ESMN1; SMN2ALDH1A1HPGDRAB9A | |
| SCHEMBL11182201 | 0.83 | PSEN1 (0.45) | TLR7PARP1KDM4EALDH1A1HPGD | |
| SCHEMBL11289272 | 0.83 | KDM4E (0.50) | PARP1KDM4ESMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL11086406 | 0.83 | PARP1 (0.46) | PARP1KDM4ESMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL11081129 | 0.82 | PARP1 (0.48) | PARP1KDM4EALDH1A1HPGDRAB9A | |
| SCHEMBL11083854 | 0.82 | PARP1 (0.46) | PARP1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4435417-A | ANTIINFLAMMATORY AGENTS | GRUPPO LEPETIT S.P.A. (IT) | 1984-03-06 | — | — | US | disclosed |
| EP-0012866-A1 | New 3H-naphtho(1,2-d)imidazoles, processes for preparing them, compounds for use as antiinflammatory and antimicrobial agents and compositions for that use containing them | GRUPPO LEPETIT S.P.A. (IT) | 1980-07-09 | — | — | EP | disclosed |