Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11086416 | 0.88 | PARP1 (0.51) | PARP1CYP3A4ALDH1A1HPGDMEN1 | |
| SCHEMBL11078271 | 0.87 | PARP1 (0.50) | PARP1CYP3A4TP53ALDH1A1HPGD | |
| SCHEMBL11075495 | 0.84 | TLR7 (0.50) | GABRA2GABRB2EGFRMAPTRAB9A | |
| SCHEMBL11078229 | 0.84 | PARP1 (0.47) | PARP1ALDH1A1HPGDMEN1MAPT | |
| SCHEMBL11080557 | 0.83 | PARP1 (0.46) | PARP1TP53MAPTDHFRSHMT2 | |
| SCHEMBL11086406 | 0.83 | PARP1 (0.46) | PARP1ALDH1A1HPGDMEN1MAPT | |
| SCHEMBL11080835 | 0.83 | PARP1 (0.46) | PARP1GABRA2GABRB2TP53ALDH1A1 | |
| SCHEMBL11076059 | 0.82 | TLR7 (0.48) | PARP1TP53ALDH1A1HPGDMEN1 | |
| SCHEMBL11083854 | 0.82 | PARP1 (0.46) | PARP1ADORA3ADORA1DHFRSHMT2 | |
| SCHEMBL11073129 | 0.82 | PARP1 (0.55) | PARP1TP53ALDH1A1HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4435417-A | ANTIINFLAMMATORY AGENTS | GRUPPO LEPETIT S.P.A. (IT) | 1984-03-06 | — | — | US | disclosed |
| EP-0012866-A1 | New 3H-naphtho(1,2-d)imidazoles, processes for preparing them, compounds for use as antiinflammatory and antimicrobial agents and compositions for that use containing them | GRUPPO LEPETIT S.P.A. (IT) | 1980-07-09 | — | — | EP | disclosed |