Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 4/20 | 0.38 |
| ▸ | PPARA | Q07869 | 4/20 | 0.38 |
| ▸ | HTR2A | P28223 | 3/20 | 0.36 |
| ▸ | HTR2C | P28335 | 3/20 | 0.36 |
| ▸ | HTR2B | P41595 | 2/20 | 0.36 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.36 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.36 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | METAP1 | P53582 | 1/20 | 0.36 |
| ▸ | HHAT | Q5VTY9 | 1/20 | 0.36 |
| ▸ | SDCBP | O00560 | 1/20 | 0.34 |
| ▸ | SDC2 | P34741 | 1/20 | 0.34 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.34 |
| ▸ | XIAP | P98170 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11083423 | 0.90 | MDM2 (0.39) | PPARGPPARAHTR2AHTR2CHTR2B | |
| SCHEMBL11078543 | 0.85 | ACHE (0.50) | PPARGPPARAHTR2AHTR2CHTR2B | |
| SCHEMBL1641257 | 0.84 | EDNRB (0.37) | HTR2AHTR2CHTR2BSLC1A3SLC1A2 | |
| SCHEMBL11084848 | 0.84 | ACHE (0.51) | PPARGPPARASLC1A3SLC1A2SLC1A1 | |
| SCHEMBL11077273 | 0.82 | HTR2A (0.39) | HTR2AHTR2CHTR2BSLC1A3SLC1A2 | |
| SCHEMBL11083966 | 0.80 | METAP1 (0.45) | PPARAHTR2AHTR2CHTR2BSLC1A3 | |
| SCHEMBL15617646 | 0.77 | HTR2A (0.41) | HTR2AHTR2CHTR2BNOTUMHTR1A | |
| SCHEMBL11085584 | 0.74 | EDNRB (0.35) | HTR2AHTR2CHTR2BSLC1A3SLC1A2 | |
| SCHEMBL11088030 | 0.74 | ACHE (0.49) | SLC1A3SLC1A2SLC1A1DRD3MDM2 | |
| SCHEMBL11080573 | 0.74 | AADAT (0.35) | PPARGPPARANOTUMHTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4443626-A | ANTIINFLAMMATORY, ANTIALLERGENS, ANALGESICS, ANTICOAGULANTS, ANTIPRETICS, OR ANTICHOLESTEROL AGENTS | HISAMITSU PHARMACEUTICAL CO., INC. (JP) | 1984-04-17 | — | — | US | claimed |
| US-4443626-A | ANTIINFLAMMATORY, ANTIALLERGENS, ANALGESICS, ANTICOAGULANTS, ANTIPRETICS, OR ANTICHOLESTEROL AGENTS | HISAMITSU PHARMACEUTICAL CO., INC. (JP) | 1984-04-17 | — | — | US | disclosed |