Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 10/20 | 0.56 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.36 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.36 |
| ▸ | CCR1 | P32246 | 1/20 | 0.35 |
| ▸ | TACR1 | P25103 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.35 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11070850 | 0.83 | OPRL1 (0.53) | OPRL1OPRM1ALDH1A1SLC6A4L3MBTL1 | |
| SCHEMBL11073882 | 0.82 | OPRL1 (0.52) | OPRL1OPRM1OPRK1OPRD1CCR1 | |
| SCHEMBL11073750 | 0.80 | OPRL1 (0.50) | OPRL1OPRM1DUSP3PTPN5PTPN11 | |
| SCHEMBL11066053 | 0.77 | OPRL1 (0.49) | OPRL1OPRM1TACR1SLC6A4 | |
| SCHEMBL11069281 | 0.77 | OPRL1 (0.46) | OPRL1OPRM1OPRK1OPRD1CCR1 | |
| SCHEMBL11077290 | 0.76 | OPRD1 (0.55) | OPRL1OPRM1OPRK1OPRD1 | |
| SCHEMBL11078979 | 0.76 | OPRL1 (0.45) | OPRL1OPRM1ALDH1A1CCR1TACR1 | |
| SCHEMBL11076835 | 0.75 | OPRL1 (0.44) | OPRL1OPRM1DUSP3PTPN11SLC6A4 | |
| SCHEMBL11075757 | 0.74 | OPRL1 (0.43) | OPRL1OPRM1CCR1TACR1SLC6A4 | |
| SCHEMBL11073972 | 0.74 | OPRL1 (0.40) | OPRL1OPRM1CCR1TACR1SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4447454-A | Analgetic compounds, compositions and process of treatment | THE UPJOHN COMPANY (US) | 1984-05-08 | — | — | US | disclosed |
| US-4113866-A | ANALGETIC COMPOUNDS, COMPOSITIONS AND PROCESS OF TREATMENT | THE UPJOHN COMPANY (US) | 1978-09-12 | — | — | US | disclosed |