Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 6/20 | 0.34 |
| ▸ | RAB9A | P51151 | 6/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1107811 | 0.90 | SMN1; SMN2 (0.39) | SMN1; SMN2HPGDL3MBTL1LMNATAAR1 | |
| SCHEMBL1107843 | 0.89 | SMN1; SMN2 (0.38) | SMN1; SMN2HPGDL3MBTL1LMNATAAR1 | |
| SCHEMBL1107824 | 0.85 | L3MBTL1 (0.43) | SMN1; SMN2L3MBTL1HTTLMNATAAR1 | |
| SCHEMBL1107849 | 0.83 | SMN1; SMN2 (0.37) | SMN1; SMN2HPGDL3MBTL1HTTLMNA | |
| SCHEMBL1107839 | 0.81 | SMN1; SMN2 (0.38) | SMN1; SMN2HPGDL3MBTL1LMNATAAR1 | |
| SCHEMBL1107807 | 0.80 | NPC1 (0.42) | SMN1; SMN2HPGDL3MBTL1LMNATAAR1 | |
| SCHEMBL1107842 | 0.79 | KMT2A (0.46) | SMN1; SMN2HPGDLMNATAAR1NPC1 | |
| SCHEMBL27866325 | 0.79 | SMN1; SMN2 (0.46) | SMN1; SMN2L3MBTL1LMNATAAR1NPC1 | |
| SCHEMBL14095750 | 0.79 | SMN1; SMN2 (0.37) | SMN1; SMN2HPGDL3MBTL1LMNATAAR1 | |
| SCHEMBL1107864 | 0.77 | ATM (0.43) | SMN1; SMN2L3MBTL1LMNATAAR1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8153560-B2 | Pesticidal active mixtures comprising aminothiazoline compounds | BASF SE (DE) | 2012-04-10 | — | — | US | disclosed |
| US-8153560-B2 | Pesticidal active mixtures comprising aminothiazoline compounds | BASF SE (DE) | 2012-04-10 | — | — | US | disclosed |
| US-20100056469-A1 | Pesticidal Active Mixtures Comprising Aminothiazoline Compounds | BASF SE (DE) | 2010-03-04 | — | — | US | disclosed |
| US-20100056469-A1 | Pesticidal Active Mixtures Comprising Aminothiazoline Compounds | BASF SE (DE) | 2010-03-04 | — | — | US | disclosed |
| WO-2008104503-A1 | PESTICIDAL ACTIVE MIXTURES COMPRISING AMINOTHIAZOLINE COMPOUNDS | BASF SE (DE) | 2008-09-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100056469-A1 | Pesticidal Active Mixtures Comprising Aminothiazoline Compounds | ACHE, PTMS, CHRM3 | SMN1; SMN2 4497/4885HPGD 4354/4885L3MBTL1 814/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.