Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | NAAA | Q02083 | 7/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11071475 | 0.95 | ABCB11 (0.45) | ABCB11LMNAMAPTMAPK1EPHX1 | |
| SCHEMBL11077615 | 0.92 | CYP1A2 (0.44) | ABCB11LMNAMAPTMAPK1EPHX1 | |
| SCHEMBL11077800 | 0.90 | ABCB11 (0.40) | ABCB11LMNAMAPTMAPK1EPHX1 | |
| SCHEMBL11071844 | 0.88 | ABCB11 (0.43) | ABCB11LMNAMAPTMAPK1EPHX1 | |
| SCHEMBL11078765 | 0.88 | ABCB11 (0.43) | ABCB11LMNAMAPTMAPK1EPHX1 | |
| SCHEMBL11080618 | 0.88 | ABCB11 (0.43) | ABCB11LMNAMAPTMAPK1EPHX1 | |
| SCHEMBL11076758 | 0.87 | ABCB11 (0.47) | ABCB11LMNAMAPTMAPK1NAAA | |
| SCHEMBL11066327 | 0.86 | ABCB11 (0.51) | ABCB11LMNAMAPTMAPK1EPHX1 | |
| SCHEMBL11075403 | 0.86 | ABCB11 (0.51) | ABCB11LMNAMAPTMAPK1EPHX1 | |
| SCHEMBL11070504 | 0.86 | SMN1; SMN2 (0.41) | ABCB11EPHX1NAAACYP1A2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4430339-A | PROPHYLAXIS, METABOLISM, GLUCOSE, FATS, HYPOGLYCEMIC AGENTS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1984-02-07 | — | — | US | disclosed |
| WO-1982000822-A1 | SUBSTITUTED OXIRANECARBOXYLIC ACIDS,THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | EISTETTER K | 1982-03-18 | — | — | WO | disclosed |