Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | NAAA | Q02083 | 2/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11077800 | 0.90 | ABCB11 (0.40) | ABCB11LMNAMAPTMAPK1NAAA | |
| SCHEMBL11071475 | 0.88 | ABCB11 (0.45) | ABCB11LMNAMAPTMAPK1NAAA | |
| SCHEMBL11078384 | 0.87 | ABCB11 (0.44) | ABCB11LMNAMAPTMAPK1ALDH1A1 | |
| SCHEMBL11070504 | 0.86 | SMN1; SMN2 (0.41) | ABCB11NAAA | |
| SCHEMBL11068114 | 0.86 | ABCB11 (0.41) | ABCB11LMNAMAPTMAPK1NAAA | |
| SCHEMBL11077615 | 0.85 | CYP1A2 (0.44) | ABCB11LMNAMAPTMAPK1NAAA | |
| SCHEMBL11156354 | 0.84 | LMNA (0.54) | ABCB11LMNAMAPTMAPK1CES2 | |
| SCHEMBL11073550 | 0.82 | ABCB11 (0.53) | ABCB11LMNAMAPTMAPK1NAAA | |
| SCHEMBL11073121 | 0.82 | ABCB11 (0.40) | ABCB11LMNAMAPTMAPK1NAAA | |
| SCHEMBL11080350 | 0.81 | ABCB11 (0.44) | ABCB11LMNAMAPTMAPK1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4430339-A | PROPHYLAXIS, METABOLISM, GLUCOSE, FATS, HYPOGLYCEMIC AGENTS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1984-02-07 | — | — | US | disclosed |