Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 5/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 4/20 | 0.31 |
| ▸ | PREP | P48147 | 1/20 | 0.31 |
| ▸ | LIPA | P38571 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.30 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.30 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1300955 | 0.86 | NAMPT (0.37) | ALDH1A1EPHX1LMNANAMPTP2RX7 | |
| SCHEMBL10058388 | 0.79 | — | — | |
| SCHEMBL11655220 | 0.79 | EPHX1 (0.48) | EPHX1NPC1KMT2AHPGDRAB9A | |
| SCHEMBL9798709 | 0.77 | EPHX1 (0.52) | EPHX1P2RX7NPC1KMT2AHPGD | |
| SCHEMBL1423045 | 0.77 | ALDH1A1 (0.38) | ALDH1A1ADRA2ASMN1; SMN2EPHX1NAMPT | |
| SCHEMBL17429993 | 0.75 | ANPEP (0.47) | ALDH1A1EPHX1NAMPTP2RX7NPC1 | |
| SCHEMBL10174290 | 0.75 | NAMPT (0.36) | ALDH1A1EPHX1NAMPTP2RX7NPC1 | |
| SCHEMBL939588 | 0.75 | ANPEP (0.47) | ALDH1A1EPHX1NAMPTP2RX7NPC1 | |
| SCHEMBL503733 | 0.75 | ANPEP (0.47) | ALDH1A1EPHX1NAMPTP2RX7NPC1 | |
| SCHEMBL1838304 | 0.73 | NAMPT (0.35) | ALDH1A1EPHX1NAMPTP2RX7NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4452813-A | BENZENESULFONYLOXY-CYCLOHEXYLALKANONES | TAIHO PHARMACEUTICAL COMPANY LIMITED (JP) | 1984-06-05 | — | — | US | disclosed |