Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 2/20 | 0.31 |
| ▸ | DRD3 | P35462 | 2/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11079381 | 0.91 | PGR (0.31) | PGRDRD2DRD3 | |
| SCHEMBL11077643 | 0.88 | — | — | |
| SCHEMBL11074662 | 0.88 | SLC6A4 (0.32) | SLC6A4SLC6A3PGRDRD2DRD3 | |
| SCHEMBL11076857 | 0.87 | — | — | |
| SCHEMBL11079751 | 0.83 | — | — | |
| SCHEMBL11074062 | 0.81 | PGR (0.35) | PGRDRD2DRD3 | |
| SCHEMBL11075041 | 0.80 | — | — | |
| SCHEMBL11073495 | 0.80 | PGR (0.33) | PGR | |
| SCHEMBL11077431 | 0.79 | OPRM1 (0.36) | — | |
| SCHEMBL11069096 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4447454-A | Analgetic compounds, compositions and process of treatment | THE UPJOHN COMPANY (US) | 1984-05-08 | — | — | US | disclosed |
| US-4113866-A | ANALGETIC COMPOUNDS, COMPOSITIONS AND PROCESS OF TREATMENT | THE UPJOHN COMPANY (US) | 1978-09-12 | — | — | US | disclosed |