Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.52 |
| ▸ | RAB9A | P51151 | 7/20 | 0.52 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.44 |
| ▸ | PTAFR | P25105 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.43 |
| ▸ | TUBB | P07437 | 1/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.43 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.43 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9434246 | 0.78 | ALDH1A1 (0.55) | NPC1RAB9AGAATDP1L3MBTL1 | |
| SCHEMBL9434253 | 0.78 | ALDH1A1 (0.55) | NPC1RAB9AGAATDP1L3MBTL1 | |
| SCHEMBL9433789 | 0.78 | ALDH1A1 (0.55) | NPC1RAB9AGAATDP1L3MBTL1 | |
| SCHEMBL11079768 | 0.76 | HTT (0.55) | NPC1RAB9AGAAL3MBTL1SMN1; SMN2 | |
| SCHEMBL11079773 | 0.76 | HTT (0.55) | NPC1RAB9AGAAL3MBTL1SMN1; SMN2 | |
| SCHEMBL9507236 | 0.76 | RAB9A (0.51) | NPC1RAB9AAGTR1OPRK1GAA | |
| SCHEMBL9507234 | 0.76 | RAB9A (0.51) | NPC1RAB9AAGTR1OPRK1GAA | |
| SCHEMBL9233936 | 0.76 | TDP1 (0.53) | NPC1RAB9ATDP1L3MBTL1SMN1; SMN2 | |
| SCHEMBL27819564 | 0.75 | RAB9A (0.51) | NPC1RAB9AAGTR1OPRK1GAA | |
| SCHEMBL6169410 | 0.73 | ALDH1A1 (0.55) | NPC1RAB9AGAASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4442100-A | ANTILIPEMIC | BAYER AKTIENGESELLSCHAFT (DE) | 1984-04-10 | — | — | US | disclosed |