Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | OPRL1 | P41146 | 16/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 13/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11070143 | 0.82 | OPRL1 (0.56) | SLC6A4SLC6A3OPRL1OPRM1 | |
| SCHEMBL11076438 | 0.81 | SLC6A4 (0.43) | SLC6A4SLC6A3OPRL1OPRM1OPRK1 | |
| SCHEMBL11065445 | 0.79 | OPRM1 (0.58) | OPRL1OPRM1OPRK1OPRD1 | |
| SCHEMBL10476540 | 0.77 | OPRM1 (0.60) | OPRL1OPRM1OPRK1OPRD1 | |
| SCHEMBL11075649 | 0.76 | SLC6A3 (0.50) | SLC6A4SLC6A3OPRL1OPRK1 | |
| SCHEMBL11078328 | 0.76 | SLC6A4 (0.47) | SLC6A4SLC6A3OPRL1OPRM1OPRK1 | |
| Hydrochloric Acid SCHEMBL1141265 | 0.75 | OPRM1 (0.58) | OPRL1OPRM1OPRK1OPRD1 | |
| SCHEMBL11073738 | 0.75 | SLC6A3 (0.49) | SLC6A4SLC6A3OPRL1OPRM1OPRK1 | |
| SCHEMBL11076078 | 0.75 | SLC6A4 (0.49) | SLC6A4SLC6A3OPRL1OPRM1OPRK1 | |
| SCHEMBL11076134 | 0.74 | HTR1D (0.38) | OPRL1OPRM1OPRK1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4447454-A | Analgetic compounds, compositions and process of treatment | THE UPJOHN COMPANY (US) | 1984-05-08 | — | — | US | disclosed |
| US-4113866-A | ANALGETIC COMPOUNDS, COMPOSITIONS AND PROCESS OF TREATMENT | THE UPJOHN COMPANY (US) | 1978-09-12 | — | — | US | disclosed |