Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.44 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.44 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.44 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11078932 | 0.93 | KMT2A (0.67) | KMT2AMEN1NPSR1TP53MAPT | |
| SCHEMBL10999619 | 0.84 | KMT2A (0.60) | KMT2AMEN1NPSR1USP2CYP1A2 | |
| SCHEMBL11079379 | 0.81 | KMT2A (0.56) | KMT2AMEN1NPSR1USP2CYP1A2 | |
| SCHEMBL10988161 | 0.75 | PIK3CA (0.50) | KMT2AMEN1NPSR1MAPTNPC1 | |
| SCHEMBL28869963 | 0.74 | MALT1 (0.48) | KMT2AMEN1NPSR1TP53MAPT | |
| SCHEMBL28279865 | 0.74 | MALT1 (0.48) | KMT2AMEN1NPSR1TP53MAPT | |
| SCHEMBL18952672 | 0.72 | NPSR1 (0.46) | KMT2AMEN1NPSR1TP53MAPT | |
| SCHEMBL11083093 | 0.72 | ADORA1 (0.57) | KMT2APTGS2 | |
| SCHEMBL4803279 | 0.71 | CNR1 (0.61) | KMT2AMEN1NPSR1USP2CYP1A2 | |
| SCHEMBL11077623 | 0.71 | ADORA1 (0.53) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4438117-A | ANALGESICS, ANTINFLAMMATORY AND ANTIARTHRITIC AGENTS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-03-20 | — | — | US | disclosed |