Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 2/20 | 0.57 |
| ▸ | PTGS2 | P35354 | 13/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.47 |
| ▸ | MAPK13 | O15264 | 4/20 | 0.40 |
| ▸ | MAPK12 | P53778 | 4/20 | 0.40 |
| ▸ | MAPK11 | Q15759 | 4/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11077623 | 0.81 | ADORA1 (0.53) | ADORA1KMT2AADORA2A | |
| SCHEMBL11078932 | 0.77 | KMT2A (0.67) | ADORA1PTGS2KMT2AADORA2A | |
| SCHEMBL7210423 | 0.73 | ADORA1 (0.51) | ADORA1MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL11078956 | 0.72 | KMT2A (0.58) | PTGS2KMT2A | |
| SCHEMBL9956075 | 0.71 | ADORA1 (0.77) | ADORA1KMT2AADORA2A | |
| SCHEMBL7210550 | 0.71 | ADORA1 (0.75) | ADORA1MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL9345348 | 0.71 | ADORA1 (0.50) | ADORA1PTGS2PTGS1MAPK13MAPK12 | |
| SCHEMBL7215179 | 0.71 | MAPK14 (0.56) | ADORA1MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL7210472 | 0.71 | MAPK14 (0.50) | ADORA1MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL7222483 | 0.71 | ADORA1 (0.75) | ADORA1MAPK13MAPK12MAPK11MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4438117-A | ANALGESICS, ANTINFLAMMATORY AND ANTIARTHRITIC AGENTS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-03-20 | — | — | US | disclosed |