Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.49 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.49 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.49 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11078956 | 0.93 | KMT2A (0.58) | KMT2AMAPTTP53TSHRMAPK1 | |
| SCHEMBL11083093 | 0.77 | ADORA1 (0.57) | KMT2APTGS2ADORA2AADORA1 | |
| SCHEMBL11077623 | 0.77 | ADORA1 (0.53) | KMT2AADORA2AADORA1 | |
| SCHEMBL10998119 | 0.76 | KMT2A (0.61) | KMT2AMAPTHTTLMNAALDH1A1 | |
| SCHEMBL9695434 | 0.76 | KMT2A (0.66) | KMT2AMAPTTP53TSHRMAPK1 | |
| SCHEMBL10999619 | 0.75 | KMT2A (0.60) | KMT2AMAPTTP53TSHRMAPK1 | |
| SCHEMBL9695584 | 0.75 | NPC1 (0.60) | KMT2AMAPTTP53TSHRMAPK1 | |
| SCHEMBL10999778 | 0.75 | KMT2A (0.60) | KMT2AMAPTTP53TSHRMAPK1 | |
| SCHEMBL5448851 | 0.74 | KMT2A (0.86) | KMT2AMAPTTP53TSHRMAPK1 | |
| SCHEMBL10820279 | 0.74 | ALDH1A1 (0.51) | KMT2AMAPTTP53LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4438117-A | ANALGESICS, ANTINFLAMMATORY AND ANTIARTHRITIC AGENTS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-03-20 | — | — | US | disclosed |