Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.54 |
| ▸ | RAB9A | P51151 | 5/20 | 0.54 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | AHR | P35869 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Anthraquinone SCHEMBL2778406 | 1.00 | NPC1 (0.54) | NPC1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL11519732 | 0.94 | NPC1 (0.44) | NPC1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL19291 | 0.94 | NPC1 (0.44) | NPC1RAB9AMAPTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL27346450 | 0.92 | NPC1 (0.42) | NPC1RAB9AMAPTMEN1KMT2A | |
| Methane SCHEMBL11523432 | 0.92 | NPC1 (0.42) | NPC1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL6890133 | 0.92 | NPC1 (0.42) | NPC1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL4674985 | 0.91 | NPC1 (0.41) | NPC1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL27707876 | 0.90 | NPC1 (0.50) | NPC1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL8949073 | 0.88 | RAB9A (0.43) | NPC1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL7094873 | 0.87 | RAB9A (0.39) | NPC1RAB9AMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4451398-A | Dyes containing imidazolymethylene groups | BASF AKTIENGESELLSCHAFT (DE) | 1984-05-29 | — | — | US | disclosed |