SCHEMBL8949073

SCHEMBL8949073

O=C1CC=Cc2nc3ccccc3cc21.O=C1c2ccccc2C(=O)c2c(Br)cccc21

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 3/20 0.43
NPC1 O15118 2/20 0.43
MAPT P10636 6/20 0.33
L3MBTL1 Q9Y468 5/20 0.33
ALDH1A1 P00352 4/20 0.33
MEN1 O00255 3/20 0.33
KMT2A Q03164 3/20 0.33
POLB P06746 1/20 0.33
HTT P42858 1/20 0.33
APEX1 P27695 1/20 0.32
ADORA2A P29274 1/20 0.32
ATM Q13315 1/20 0.32
MAPK1 P28482 4/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
CYP3A4 P08684 2/20 0.32
KDM4E B2RXH2 1/20 0.32
TP53 P04637 1/20 0.32
CYP2D6 P10635 1/20 0.32
CYP2C9 P11712 1/20 0.32
PKM P14618 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Anthraquinone SCHEMBL2778406 0.88 NPC1 (0.54) RAB9ANPC1MAPTL3MBTL1ALDH1A1
Anthraquinone SCHEMBL11078992 0.88 NPC1 (0.54) RAB9ANPC1MAPTL3MBTL1ALDH1A1
SCHEMBL8949329 0.85 NPC1 (0.40) RAB9ANPC1
SCHEMBL19291 0.83 NPC1 (0.44) RAB9ANPC1MAPTL3MBTL1ALDH1A1
SCHEMBL11519732 0.83 NPC1 (0.44) RAB9ANPC1MAPTL3MBTL1ALDH1A1
Hydrochloric Acid SCHEMBL27346450 0.81 NPC1 (0.42) RAB9ANPC1MAPTL3MBTL1ALDH1A1
SCHEMBL6890133 0.81 NPC1 (0.42) RAB9ANPC1MAPTL3MBTL1ALDH1A1
Methane SCHEMBL11523432 0.81 NPC1 (0.42) RAB9ANPC1MAPTL3MBTL1ALDH1A1
SCHEMBL4674985 0.80 NPC1 (0.41) RAB9ANPC1MAPTL3MBTL1ALDH1A1
SCHEMBL27707876 0.79 NPC1 (0.50) RAB9ANPC1MAPTALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5525743-A Preparation of anthraquinone imide compounds BASF AKTIENGESELLSCHAFT (DE) 1996-06-11 US disclosed