Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 1/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.31 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.31 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.31 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.31 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.31 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11077331 | 0.87 | KCNN4 (0.35) | KCNN4PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL11069388 | 0.79 | SLC6A4 (0.33) | OPRM1 | |
| SCHEMBL11077717 | 0.78 | OPRM1 (0.36) | OPRM1 | |
| SCHEMBL11073309 | 0.77 | SLC6A4 (0.31) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL11073838 | 0.76 | KCNN4 (0.32) | KCNN4 | |
| SCHEMBL11090331 | 0.76 | MAOA (0.38) | OPRM1 | |
| SCHEMBL11070605 | 0.76 | MAOA (0.38) | OPRM1 | |
| SCHEMBL11096526 | 0.76 | MAOA (0.38) | OPRM1 | |
| SCHEMBL11072605 | 0.76 | SLC6A4 (0.41) | KCNN4 | |
| SCHEMBL11073833 | 0.76 | KCNN4 (0.32) | KCNN4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4447454-A | Analgetic compounds, compositions and process of treatment | THE UPJOHN COMPANY (US) | 1984-05-08 | — | — | US | disclosed |
| US-4113866-A | ANALGETIC COMPOUNDS, COMPOSITIONS AND PROCESS OF TREATMENT | THE UPJOHN COMPANY (US) | 1978-09-12 | — | — | US | disclosed |