Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | PIM1 | P11309 | 2/20 | 0.46 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.46 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.46 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1107905 | 0.97 | MEN1 (0.53) | MEN1KMT2ARAB9APIM1PIM3 | |
| SCHEMBL1107866 | 0.96 | RAB9A (0.57) | MEN1KMT2ARAB9APIM1PIM3 | |
| SCHEMBL1107895 | 0.93 | RAB9A (0.67) | MEN1KMT2ARAB9APIM1PIM3 | |
| SCHEMBL1107892 | 0.91 | RAB9A (0.59) | MEN1KMT2ARAB9APIM1PIM3 | |
| SCHEMBL1107876 | 0.88 | KMT2A (0.44) | MEN1KMT2ARAB9APIM1PIM3 | |
| SCHEMBL1107862 | 0.87 | RAB9A (0.50) | MEN1KMT2ARAB9APIM1PIM3 | |
| SCHEMBL1107931 | 0.85 | KIF11 (0.46) | MEN1KMT2ARAB9APIM1PIM3 | |
| SCHEMBL1107915 | 0.84 | RAB9A (0.55) | MEN1KMT2ARAB9APIM1PIM3 | |
| SCHEMBL1107848 | 0.83 | KDM4E (0.56) | MEN1KMT2ARAB9AHSD17B1MAPT | |
| SCHEMBL1107883 | 0.83 | KDM4E (0.56) | MEN1KMT2ARAB9AHSD17B1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8153277-B2 | Compound having thiadiazole ring structure substituted with pyridyl group and organic electroluminescent device | HODOGAYA CHEMICAL CO., LTD. (JP) | 2012-04-10 | — | — | US | disclosed |
| US-8153277-B2 | Compound having thiadiazole ring structure substituted with pyridyl group and organic electroluminescent device | HODOGAYA CHEMICAL CO., LTD. (JP) | 2012-04-10 | — | — | US | disclosed |
| US-20090108750-A1 | COMPOUND HAVING THIADIAZOLE RING STRUCTURE SUBSTITUTED WITH PYRIDYL GROUP AND ORGANIC ELECTROLUMINESCENT DEVICE | HODOGAYA CHEMICAL CO., LTD. (JP) | 2009-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090108750-A1 | COMPOUND HAVING THIADIAZOLE RING STRUCTURE SUBSTITUTED WITH PYRIDYL GROUP AND ORGANIC ELECTROLUMINESCENT DEVICE | OXA1L, SLCO4C1, SLCO2B1 | MEN1 1449/4885KMT2A 2715/4885RAB9A 2662/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.