Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 4/20 | 0.49 |
| ▸ | ALKBH2 | Q6NS38 | 1/20 | 0.42 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.38 |
| ▸ | EP300 | Q09472 | 1/20 | 0.37 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21863293 | 0.78 | GRM5 (0.47) | GRM5ALKBH2EGLN1POLBSMN1; SMN2 | |
| SCHEMBL5204921 | 0.77 | GRM5 (0.46) | GRM5ALKBH2EGLN1POLBSMN1; SMN2 | |
| SCHEMBL13045111 | 0.77 | SMN1; SMN2 (0.47) | GRM5ALKBH2EGLN1POLBSMN1; SMN2 | |
| SCHEMBL2550402 | 0.77 | GRM5 (0.46) | GRM5ALKBH2EGLN1POLBSMN1; SMN2 | |
| SCHEMBL6450046 | 0.76 | GRM5 (0.49) | GRM5ALKBH2EGLN1POLBSMN1; SMN2 | |
| SCHEMBL21816065 | 0.75 | ALKBH2 (0.53) | GRM5ALKBH2EGLN1POLBSMN1; SMN2 | |
| SCHEMBL31133407 | 0.75 | ALKBH2 (0.53) | GRM5ALKBH2EGLN1POLBSMN1; SMN2 | |
| SCHEMBL6450076 | 0.74 | GRM5 (0.65) | GRM5ALKBH2EGLN1POLBSMN1; SMN2 | |
| SCHEMBL7152205 | 0.74 | GRM5 (0.54) | GRM5ALKBH2EGLN1POLBSMN1; SMN2 | |
| SCHEMBL17324654 | 0.74 | ROCK1 (0.46) | GRM5ALKBH2EGLN1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4400516-A | PYRIDINE OR QUINOLINE SUBSTITUTED PESTICIDES | THE DOW CHEMICAL CO. (US) | 1983-08-23 | — | — | US | claimed |
| US-4451653-A | INSECTICIDCES | THE DOW CHEMICAL COMPANY (US) | 1984-05-29 | — | — | US | disclosed |
| US-4433148-A | CHEMICAL INTERMEDIATES FOR TRIAZOLYL PHOSPHORUS INSECTICIDWS | THE DOW CHEMICAL CO. (US) | 1984-02-21 | — | — | US | disclosed |
| US-4400516-A | PYRIDINE OR QUINOLINE SUBSTITUTED PESTICIDES | THE DOW CHEMICAL CO. (US) | 1983-08-23 | — | — | US | disclosed |
| US-4357327-A | Heterocyclic substituted triazolyl phosphorous compounds and their use as insecticides | THE DOW CHEMICAL CO. (US) | 1982-11-02 | — | — | US | disclosed |
| US-4357328-A | Heterocyclic substituted triazolyl phosphorous compounds and their use as insecticides | THE DOW CHEMICAL CO. (US) | 1982-11-02 | — | — | US | disclosed |
| EP-0010891-B1 | HETEROCYCLIC SUBSTITUTED TRIAZOLYL PHOSPHOROUS COMPOUNDS, INSECTICIDAL COMPOSITIONS CONTAINING THEM AND METHOD FOR CONTROLLING INSECTS | THE DOW CHEMICAL COMPANY (US) | 1982-09-01 | — | — | EP | disclosed |
| US-4298602-A | MITICIDES | THE DOW CHEMICAL COMPANY (US) | 1981-11-03 | — | — | US | disclosed |
| EP-0010891-A1 | Heterocyclic substituted triazolyl phosphorous compounds, insecticidal compositions containing them and method for controlling insects | THE DOW CHEMICAL COMPANY (US) | 1980-05-14 | — | — | EP | disclosed |