Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SLC6A12 | P48065 | 4/20 | 0.36 |
| ▸ | SLC6A11 | P48066 | 4/20 | 0.36 |
| ▸ | SLC6A13 | Q9NSD5 | 4/20 | 0.36 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.36 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7359680 | 0.88 | TSHR (0.36) | TSHRSLC6A12SLC6A11SLC6A13ALDH1A1 | |
| Acetic Acid SCHEMBL6185642 | 0.80 | POLB (0.32) | POLB | |
| SCHEMBL11126941 | 0.79 | TSHR (0.35) | TSHRSLC6A12SLC6A11SLC6A13SLC6A1 | |
| SCHEMBL6628398 | 0.76 | EPHX2 (0.33) | — | |
| SCHEMBL2558996 | 0.74 | NCF1 (0.43) | TSHRSLC6A12SLC6A11SLC6A13SLC6A1 | |
| SCHEMBL16120530 | 0.74 | NCF1 (0.33) | — | |
| SCHEMBL1108993 | 0.74 | NCF1 (0.43) | TSHRSLC6A12SLC6A11SLC6A13SLC6A1 | |
| SCHEMBL805205 | 0.74 | NCF1 (0.48) | TSHRSLC6A12SLC6A11SLC6A13SLC6A1 | |
| SCHEMBL6271269 | 0.74 | ACE (0.38) | — | |
| SCHEMBL6185643 | 0.74 | CHRNB2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4447434-A | ANTIULCER, ANTISECRETORY, OR ANTICHOLINERGIC AGENTS | DR. KARL THOMAE GMBH (DE) | 1984-05-08 | — | — | US | disclosed |