Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 6/20 | 0.83 |
| ▸ | TSHR | P16473 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.43 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | GBA1 | P04062 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alcohol SCHEMBL28079192 | 0.97 | DNM1 (0.84) | DNM1TSHRALDH1A1LMNAHSD17B10 | |
| Alcohol SCHEMBL28217331 | 0.97 | DNM1 (0.84) | DNM1TSHRALDH1A1LMNAHSD17B10 | |
| Alcohol SCHEMBL29264755 | 0.97 | DNM1 (0.84) | DNM1TSHRALDH1A1LMNAHSD17B10 | |
| Dymanthine SCHEMBL11078579 | 0.97 | DNM1 (0.84) | DNM1TSHRALDH1A1LMNAHSD17B10 | |
| Alcohol SCHEMBL6546105 | 0.97 | DNM1 (0.84) | DNM1TSHRALDH1A1LMNAHSD17B10 | |
| Methyl Alcohol SCHEMBL28187785 | 0.92 | DNM1 (0.88) | DNM1TSHRALDH1A1LMNAHSD17B10 | |
| SCHEMBL25269808 | 0.91 | DNM1 (1.00) | DNM1TSHRALDH1A1THRBCA12 | |
| SCHEMBL10407867 | 0.91 | DNM1 (1.00) | DNM1TSHRALDH1A1THRBCA12 | |
| SCHEMBL9807727 | 0.91 | DNM1 (1.00) | DNM1TSHRALDH1A1THRBCA12 | |
| Dymanthine SCHEMBL61784 | 0.91 | DNM1 (1.00) | DNM1TSHRALDH1A1THRBCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105948670-A | Ecologically and environment-friendly type diatomite mortar used for inner wall board | 安徽惠明建材科技发展有限公司 | 2016-09-21 | — | — | CN | claimed |
| CN-108721644-A | A kind of taxone method for preparing lipidosome | 常州金远药业制造有限公司 | 2018-11-02 | — | — | CN | disclosed |
| CN-105948670-A | Ecologically and environment-friendly type diatomite mortar used for inner wall board | 安徽惠明建材科技发展有限公司 | 2016-09-21 | — | — | CN | disclosed |
| US-4434076-A | QUATERNARY AMMONIUM-SMECTITE COMPLEXES | NL INDUSTRIES, INC. (US) | 1984-02-28 | — | — | US | disclosed |