Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 6/20 | 0.84 |
| ▸ | TSHR | P16473 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.42 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GBA1 | P04062 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alcohol SCHEMBL28079192 | 1.00 | DNM1 (0.84) | DNM1TSHRALDH1A1LMNAHSD17B10 | |
| Alcohol SCHEMBL11079571 | 0.97 | DNM1 (0.83) | DNM1TSHRALDH1A1LMNAHSD17B10 | |
| Alcohol SCHEMBL6546105 | 0.95 | DNM1 (0.84) | DNM1TSHRALDH1A1LMNAHSD17B10 | |
| Alcohol SCHEMBL29264755 | 0.95 | DNM1 (0.84) | DNM1TSHRALDH1A1LMNAHSD17B10 | |
| Dymanthine SCHEMBL11078579 | 0.95 | DNM1 (0.84) | DNM1TSHRALDH1A1LMNAHSD17B10 | |
| Ethylene Glycol SCHEMBL28217431 | 0.92 | DNM1 (0.80) | DNM1TSHRALDH1A1LMNAHSD17B10 | |
| Bromide SCHEMBL21247774 | 0.92 | DNM1 (1.00) | DNM1TSHRALDH1A1CA12CA1 | |
| Bromide SCHEMBL3014917 | 0.92 | DNM1 (1.00) | DNM1TSHRALDH1A1CA12CA1 | |
| Bromide SCHEMBL21293896 | 0.92 | DNM1 (1.00) | DNM1TSHRALDH1A1CA12CA1 | |
| Bromide SCHEMBL21293895 | 0.92 | DNM1 (1.00) | DNM1TSHRALDH1A1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108086019-A | A kind of preparation method for being packed for polyester fabric dedicated dye | 明光市永德包装有限公司 | 2018-05-29 | — | — | CN | claimed |