Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 3/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.41 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 3/20 | 0.39 |
| ▸ | TMPRSS11D | O60235 | 2/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | PLG | P00747 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PRCP | P42785 | 1/20 | 0.38 |
| ▸ | ACE | P12821 | 1/20 | 0.38 |
| ▸ | PREP | P48147 | 3/20 | 0.38 |
| ▸ | FKBP1A | P62942 | 4/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11430263 | 0.95 | DPP4 (0.42) | DPP4DPP8DPP9DPP7F2 | |
| SCHEMBL7353231 | 0.81 | HTT (0.41) | DPP8DPP7 | |
| SCHEMBL11009035 | 0.80 | HTR2C (0.39) | DPP4DPP8DPP9DPP7KMT2A | |
| SCHEMBL7761092 | 0.79 | DPP4 (0.46) | DPP4DPP8DPP9DPP7F2 | |
| SCHEMBL9314043 | 0.76 | DPP8 (0.41) | DPP4DPP8DPP9DPP7 | |
| SCHEMBL9407277 | 0.76 | F2 (0.38) | DPP4DPP8DPP9DPP7F2 | |
| SCHEMBL9128839 | 0.75 | LTA4H (0.40) | DPP4DPP8DPP9DPP7 | |
| SCHEMBL9407310 | 0.74 | DPP4 (0.38) | DPP4DPP8DPP9DPP7F2 | |
| SCHEMBL9407285 | 0.74 | PREP (0.37) | DPP4DPP8DPP9DPP7F10 | |
| SCHEMBL1617501 | 0.74 | DPP4 (0.42) | DPP4F2ACEFKBP1ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4463090-A | PROENZYMES COUPLED TO LIGANDS; ACTIVATION; SENSITIVITY | RAPIDEX LIMITED | 1984-07-31 | — | — | US | disclosed |