Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 1/20 | 0.49 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.41 |
| ▸ | TACR1 | P25103 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11076003 | 0.91 | OPRD1 (0.47) | OPRD1OPRL1OPRM1SLC6A4SLC22A1 | |
| SCHEMBL11077290 | 0.89 | OPRD1 (0.55) | OPRD1OPRL1OPRM1OPRK1 | |
| SCHEMBL11076056 | 0.89 | OPRD1 (0.45) | OPRD1OPRL1OPRM1 | |
| SCHEMBL11066674 | 0.89 | OPRD1 (0.47) | OPRD1OPRL1OPRM1SLC6A4SLC22A1 | |
| SCHEMBL11079586 | 0.88 | OPRM1 (0.46) | OPRD1OPRM1 | |
| SCHEMBL11076919 | 0.88 | OPRL1 (0.43) | OPRD1OPRL1OPRM1SLC6A4OPRK1 | |
| SCHEMBL11070427 | 0.87 | OPRM1 (0.46) | OPRD1OPRL1OPRM1SLC6A4OPRK1 | |
| SCHEMBL11075277 | 0.84 | OPRL1 (0.43) | OPRD1OPRL1OPRM1SLC6A4OPRK1 | |
| SCHEMBL11070497 | 0.82 | OPRM1 (0.40) | OPRL1OPRM1OPRK1 | |
| SCHEMBL11076093 | 0.80 | OPRL1 (0.50) | OPRD1OPRL1OPRM1SLC6A4ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4447454-A | Analgetic compounds, compositions and process of treatment | THE UPJOHN COMPANY (US) | 1984-05-08 | — | — | US | disclosed |
| US-4113866-A | ANALGETIC COMPOUNDS, COMPOSITIONS AND PROCESS OF TREATMENT | THE UPJOHN COMPANY (US) | 1978-09-12 | — | — | US | disclosed |