Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.37 |
| ▸ | TOP2A | P11388 | 2/20 | 0.32 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3079790 | 0.77 | SMN1; SMN2 (0.46) | LMNAKDM4ECYP2C19NPSR1TSHR | |
| SCHEMBL14235092 | 0.77 | — | — | |
| Bemegride SCHEMBL601065 | 0.76 | LMNA (1.00) | LMNAKDM4ECYP2C19NPSR1TSHR | |
| SCHEMBL7435181 | 0.74 | KDM4E (0.40) | LMNAKDM4ECYP2C19NPSR1TSHR | |
| SCHEMBL1186756 | 0.72 | KDM4E (0.37) | LMNAKDM4ECYP2C19NPSR1TSHR | |
| SCHEMBL18826462 | 0.72 | KDM4E (0.43) | LMNAKDM4ECYP2C19NPSR1TSHR | |
| SCHEMBL4998703 | 0.70 | KDM4E (0.36) | LMNAKDM4ECYP2C19NPSR1TSHR | |
| SCHEMBL10676973 | 0.69 | KDM4E (0.39) | LMNAKDM4ECYP2C19NPSR1TSHR | |
| SCHEMBL3706662 | 0.69 | TSHR (0.58) | LMNAKDM4ECYP2C19NPSR1TSHR | |
| SCHEMBL29020997 | 0.68 | SMN1; SMN2 (0.38) | LMNAKDM4ECYP2C19NPSR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4452799-A | NEUROLEPTIC AGENTS | MEAD JOHNSON & COMPANY (US) | 1984-06-05 | — | — | US | disclosed |
| US-4411901-A | ANTIPSYCHOTICS | MEAD JOHNSON & COMPANY (US) | 1983-10-25 | — | — | US | disclosed |