Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCL8 | P10145 | 3/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.43 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.43 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.41 |
| ▸ | PYGL | P06737 | 1/20 | 0.40 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycine SCHEMBL11334765 | 0.91 | PTGS2 (0.44) | CXCL8MAPK14PDK1PDK2PDK3 | |
| SCHEMBL11761427 | 0.90 | CXCL8 (0.44) | CXCL8PDK1PDK2PDK3PDK4 | |
| SCHEMBL1677057 | 0.89 | MAPK1 (0.47) | MAPK1MEN1LMNAKMT2ANLRP3 | |
| SCHEMBL6264671 | 0.89 | MAPK1 (0.47) | MAPK1MEN1LMNAKMT2ANLRP3 | |
| SCHEMBL8039768 | 0.89 | MAPK1 (0.47) | MAPK1MEN1LMNAKMT2ANLRP3 | |
| SCHEMBL11338250 | 0.88 | CXCL8 (0.43) | CXCL8MAPK14PDK1PDK2PDK3 | |
| SCHEMBL11338246 | 0.88 | CXCL8 (0.43) | CXCL8MAPK14PDK1PDK2PDK3 | |
| SCHEMBL11347040 | 0.86 | HTT (0.43) | CXCL8MAPK14PDK1PDK2PDK3 | |
| SCHEMBL11347039 | 0.86 | HTT (0.43) | CXCL8MAPK14PDK1PDK2PDK3 | |
| SCHEMBL11336321 | 0.84 | MAPK1 (0.43) | CXCL8MAPK14PDK1PDK2PDK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0046497-B1 | N-DISUBSTITUTED ANILINE DERIVATIVES, THEIR PREPARATION, THEIR USE AS MICROBICIDES, AND COMPOSITIONS | BASF Aktiengesellschaft (DE) | 1984-11-28 | — | — | EP | disclosed |
| US-4410538-A | THIADIAZOLYLCARBONYL-CUBSTITUTED | BASF AKTIENGESELLSCHAFT (DE) | 1983-10-18 | — | — | US | disclosed |
| EP-0046497-A2 | N-disubstituted aniline derivatives, their preparation, their use as microbicides, and compositions | BASF Aktiengesellschaft (DE) | 1982-03-03 | — | — | EP | disclosed |
| US-4032657-A | FUNGICIDES | CIBA-GEIGY CORPORATION (US) | 1977-06-28 | — | — | US | disclosed |