SCHEMBL11079829

SCHEMBL11079829

COc1ccc(CC(C)(N)OC)cc1OC

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 2/20 0.55
CYP19A1 P11511 1/20 0.54
ATM Q13315 2/20 0.53
KDM4E B2RXH2 1/20 0.53
AOC3 Q16853 1/20 0.47
ALDH1A1 P00352 3/20 0.47
PPARG P37231 1/20 0.47
PPARD Q03181 1/20 0.47
PPARA Q07869 1/20 0.47
POLB P06746 2/20 0.46
CYP1A2 P05177 1/20 0.46
CYP3A4 P08684 1/20 0.46
CYP2D6 P10635 1/20 0.46
HPGD P15428 1/20 0.45
BLM P54132 1/20 0.45
PMP22 Q01453 1/20 0.45
KMT2A Q03164 1/20 0.44
LDHA P00338 1/20 0.44
CA12 O43570 1/20 0.43
CA1 P00915 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11754355 0.86 CYP19A1 (0.40) CA2CYP19A1ATMKDM4EAOC3
SCHEMBL11258047 0.85 CA2 (0.59) CA2CYP19A1ATMKDM4EAOC3
SCHEMBL27460450 0.85 CYP19A1 (0.39) CA2CYP19A1ATMKDM4EALDH1A1
Hydrochloric Acid SCHEMBL11329627 0.84 CA2 (0.57) CA2CYP19A1ATMKDM4EAOC3
Bromide SCHEMBL7199779 0.83 CYP19A1 (0.38) CA2CYP19A1ATMKDM4EALDH1A1
SCHEMBL11616934 0.82 CA2 (0.55) CA2CYP19A1ATMKDM4EAOC3
SCHEMBL10730478 0.81 CA2 (0.59) CA2CYP19A1ATMKDM4EAOC3
SCHEMBL27968678 0.81 LDHA (0.51) CA2CYP19A1ATMKDM4EALDH1A1
SCHEMBL74008 0.81 CA2 (0.63) CA2CYP19A1ATMKDM4EAOC3
SCHEMBL5114730 0.79 CA2 (0.61) CA2CYP19A1ATMKDM4EAOC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-55028915-A None JP disclosed
US-4490392-A Benzylalcohol derivative and process for preparing TANABE SEIYAKU CO., LTD. (JP) 1984-12-25 US disclosed
JP-S5528915-A BENZYL ALCOHOL DERIVATIVE AND ITS PREPARATION TANABE SEIYAKU CO LTD 1980-02-29 JP disclosed