SCHEMBL11079876

SCHEMBL11079876

CC=C(CC)Oc1ccc([N+](=O)[O-])cc1Cl

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.51
ALDH1A1 P00352 4/20 0.51
LMNA P02545 4/20 0.51
KMT2A Q03164 4/20 0.51
NPSR1 Q6W5P4 1/20 0.51
HSD17B10 Q99714 1/20 0.50
RAB9A P51151 2/20 0.49
HPGD P15428 4/20 0.48
SMN1; SMN2 Q16637 3/20 0.48
NPC1 O15118 1/20 0.48
CYP1A2 P05177 1/20 0.48
CYP3A4 P08684 1/20 0.48
CYP2D6 P10635 1/20 0.48
CYP2C9 P11712 1/20 0.48
CYP2C19 P33261 1/20 0.48
HGFAC Q04756 1/20 0.47
PDE7A Q13946 1/20 0.47
MEN1 O00255 2/20 0.46
GAA P10253 1/20 0.46
PKM P14618 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6825719 0.89 HSD17B10 (0.46) MAPTALDH1A1LMNAKMT2ANPSR1
SCHEMBL7778632 0.83 MAPT (0.55) MAPTALDH1A1LMNAKMT2ANPSR1
SCHEMBL28463968 0.78 KMT2A (0.58) MAPTALDH1A1LMNAKMT2ANPSR1
SCHEMBL28193616 0.77 HSD17B10 (0.61) MAPTALDH1A1LMNAKMT2ANPSR1
SCHEMBL7186306 0.76 HSD17B10 (0.59) MAPTALDH1A1LMNAKMT2ANPSR1
SCHEMBL28193618 0.76 HSD17B10 (0.59) MAPTALDH1A1LMNAKMT2ANPSR1
SCHEMBL6816187 0.76 MAPT (0.79) MAPTALDH1A1LMNAKMT2ANPSR1
SCHEMBL2923784 0.75 MAPT (0.59) MAPTALDH1A1LMNAKMT2ANPSR1
SCHEMBL29130743 0.75 HGFAC (0.62) MAPTALDH1A1LMNAKMT2ANPSR1
SCHEMBL18204998 0.74 RAB9A (0.57) MAPTALDH1A1LMNAKMT2ANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4427596-A POSTEMERGENCE HERBICIDES; NONPHYTOTOXIC; SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1984-01-24 US disclosed
EP-0037106-A2 N-(2-(cyclopropyl)ethoxy)phenylanilide derivatives, their production, herbicidal compositions and their use, N-(2-(cyclopropyl)ethoxy)-aniline compounds and N-(2-(cyclopropyl)ethoxy)nitrobenzene compounds SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1981-10-07 EP disclosed