Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | GPR35 | Q9HC97 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | ERN1 | O75460 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30490230 | 0.82 | TDP1 (0.57) | TDP1TSHRMAPK1VCAM1CYP3A4 | |
| SCHEMBL8013048 | 0.82 | TDP1 (0.57) | TDP1TSHRMAPK1VCAM1CYP3A4 | |
| SCHEMBL5595026 | 0.80 | TDP1 (0.67) | TDP1GPR35TSHRMAPK1VCAM1 | |
| SCHEMBL31170798 | 0.80 | TDP1 (0.67) | TDP1GPR35TSHRMAPK1VCAM1 | |
| SCHEMBL29417506 | 0.80 | TDP1 (0.67) | TDP1GPR35TSHRMAPK1VCAM1 | |
| SCHEMBL27718719 | 0.80 | HPGD (0.55) | TDP1GPR35TSHRMAPK1CYP3A4 | |
| SCHEMBL521166 | 0.80 | GPR35 (0.54) | TDP1GPR35TSHRMAPK1VCAM1 | |
| SCHEMBL306584 | 0.80 | TDP1 (0.67) | TDP1GPR35TSHRMAPK1VCAM1 | |
| SCHEMBL11868759 | 0.78 | TDP1 (0.53) | TDP1GPR35TSHRMAPK1VCAM1 | |
| SCHEMBL28781888 | 0.78 | TDP1 (0.49) | TDP1TSHRMAPK1VCAM1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-58052290-A | — | — | None | — | — | JP | disclosed |
| EP-0047005-B1 | BENZOXAZINE DERIVATIVES | DAIICHI SEIYAKU CO., LTD. (JP) | 1984-11-14 | — | — | EP | disclosed |
| US-4382892-A | Benzoxazine derivatives | DAIICHI SEIYAKU CO., LTD. (JP) | 1983-05-10 | — | — | US | disclosed |
| JP-S5852290-A | PYRIDOBENZOXAZINECARBOXYLIC ACID DERIVATIVE | DAI ICHI SEIYAKU CO LTD | 1983-03-28 | — | — | JP | disclosed |
| EP-0047005-A1 | Benzoxazine derivatives | DAIICHI SEIYAKU CO., LTD. (JP) | 1982-03-10 | — | — | EP | disclosed |
| JP-S05852290-A | — | — | 0001-01-01 | — | — | JP | disclosed |