Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.67 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | VCAM1 | P19320 | 7/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.41 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.41 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | HTR2C | P28335 | 2/20 | 0.41 |
| ▸ | HTR2B | P41595 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29417506 | 1.00 | TDP1 (0.67) | TDP1TSHRMAPK1ATMVCAM1 | |
| SCHEMBL8013048 | 0.85 | TDP1 (0.57) | TDP1TSHRMAPK1ATMVCAM1 | |
| SCHEMBL30490230 | 0.85 | TDP1 (0.57) | TDP1TSHRMAPK1ATMVCAM1 | |
| SCHEMBL3723529 | 0.83 | TDP1 (0.55) | TDP1TSHRMAPK1ATMVCAM1 | |
| SCHEMBL31342321 | 0.83 | TDP1 (0.55) | TDP1TSHRMAPK1ATMVCAM1 | |
| SCHEMBL4603872 | 0.83 | TDP1 (0.67) | TDP1TSHRMAPK1ATMVCAM1 | |
| SCHEMBL29435969 | 0.83 | TDP1 (0.67) | TDP1TSHRMAPK1ATMVCAM1 | |
| SCHEMBL278488 | 0.80 | TDP1 (1.00) | TDP1TSHRMAPK1VCAM1ALDH1A1 | |
| SCHEMBL17610001 | 0.80 | TDP1 (0.52) | TDP1TSHRMAPK1ATMVCAM1 | |
| SCHEMBL11079893 | 0.80 | TDP1 (0.52) | TDP1TSHRMAPK1ATMVCAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112142567-B | Preparation method of 2-fluoro-3-chlorophenol | 浙江永太科技股份有限公司 | 2023-11-14 | — | — | CN | claimed |
| CN-112047804-B | Preparation method of 3, 5-dichloro-4-fluorobromobenzene compound | 内蒙古永太化学有限公司 | 2023-06-27 | — | — | CN | claimed |
| CN-112010733-B | Preparation method of 3,4, 5-trifluorobromobenzene | 新岸诺亚（北京）催化科技有限公司 | 2022-08-02 | — | — | CN | claimed |
| CN-113166004-A | Method for preparing 5-bromo-1, 3-dichloro-2-fluorobenzene | 巴斯夫欧洲公司 | 2021-07-23 | — | — | CN | claimed |
| CN-112142567-A | Preparation method of 2-fluoro-3-chlorophenol | 浙江永太科技股份有限公司 | 2020-12-29 | — | — | CN | claimed |
| CN-112047804-A | Preparation method of 3, 5-dichloro-4-fluorobromobenzene compound | 内蒙古永太化学有限公司 | 2020-12-08 | — | — | CN | claimed |
| CN-112010733-A | Preparation method of 3,4, 5-trifluorobromobenzene | 新岸诺亚（北京）催化科技有限公司 | 2020-12-01 | — | — | CN | claimed |
| CN-104496824-B | A kind of method using o-dichlorohenzene as raw material coproduction QNS key intermediate | 滨海永太医化有限公司 | 2017-09-29 | — | — | CN | claimed |
| CN-104496824-A | Method for combined production of quinolone medicine key intermediate by taking o-dichlorobenzene as raw material | ZHEJIANG YONGTAI TECHNOLOGY CO LTD | 2015-04-08 | — | — | CN | claimed |
| CN-102911080-B | Method for preparing 2,6-dichloro-alpha-(4-chlorphenyl)-4-nitro phenylacetonitrile | UNIV QUZHOU | 2015-01-21 | — | — | CN | claimed |
| CN-103420842-B | Preparation method for 2,3,4-trifluoronitrobenzene | SHANGYU LINJIANG CHEMICAL CO LTD | 2015-01-07 | — | — | CN | claimed |
| EP-0635482-B1 | Process for the preparation of polyfluoronitrobenzenes | CLARIANT GMBH (DE) | 1998-10-14 | — | — | EP | claimed |
| US-5502260-A | Process for preparing multiply fluorinated nitrobenzenes | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-03-26 | — | — | US | claimed |
| EP-0635482-A2 | Process for the preparation of polyfluoronitrobenzenes | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-01-25 | — | — | EP | claimed |
| EP-0557878-A1 | Process for the selective dehalogenation of ortho-halogenated nitrobenzenes | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-09-01 | — | — | EP | claimed |
| JP-60197640-A | — | — | None | — | — | JP | disclosed |
| JP-58135840-A | — | — | None | — | — | JP | disclosed |
| US-4382892-A | Benzoxazine derivatives | DAIICHI SEIYAKU CO., LTD. (JP) | 1983-05-10 | — | — | US | disclosed |
| JP-S5852290-A | PYRIDOBENZOXAZINECARBOXYLIC ACID DERIVATIVE | DAI ICHI SEIYAKU CO LTD | 1983-03-28 | — | — | JP | disclosed |
| JP-S05852290-A | — | — | 0001-01-01 | — | — | JP | disclosed |