SCHEMBL1108014

SCHEMBL1108014

C=CC(=O)OCCC(C)CCC(C)(C)C

nearest known ligand 0.46

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.46
HPGD P15428 1/20 0.44
ALDH1A1 P00352 4/20 0.44
TP53 P04637 3/20 0.44
HIF1A Q16665 3/20 0.44
CYP3A4 P08684 3/20 0.44
HSD17B10 Q99714 1/20 0.44
THRB P10828 2/20 0.41
MAPK1 P28482 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
ALOX15 P16050 2/20 0.39
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
TDP1 Q9NUW8 2/20 0.33
LMNA P02545 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9103359 0.88 TSHR (0.57) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL231256 0.85 TSHR (0.47) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL304930 0.83 TSHR (0.45) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL1899131 0.81 TSHR (0.58) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL12266939 0.81 ALOX15 (0.59) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL7740688 0.81 TSHR (0.59) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL12198799 0.81 TSHR (0.55) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL1015244 0.80 TSHR (0.56) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL13024812 0.79 TSHR (0.39) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL8902178 0.79 TSHR (0.55) TSHRHPGDALDH1A1TP53HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8153246-B2 Optical compensatory film, polarizing plate, and liquid crystal display device FUJIFILM CORPORATION (JP) 2012-04-10 US disclosed
US-8153246-B2 Optical compensatory film, polarizing plate, and liquid crystal display device FUJIFILM CORPORATION (JP) 2012-04-10 US disclosed
US-20090273740-A1 OPTICAL COMPENSATORY FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2009-11-05 US disclosed
US-20090273740-A1 OPTICAL COMPENSATORY FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2009-11-05 US disclosed
WO-2007037497-A9 OPTICAL COMPENSATORY FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE FUJI FILM CORP (JP) 2007-05-24 WO disclosed
WO-2007037497-A1 OPTICAL COMPENSATORY FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2007-04-05 WO disclosed