Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.59 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.52 |
| ▸ | MMP2 | P08253 | 1/20 | 0.52 |
| ▸ | MMP13 | P45452 | 1/20 | 0.52 |
| ▸ | CKS1B | P61024 | 1/20 | 0.51 |
| ▸ | SKP1 | P63208 | 1/20 | 0.51 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27723124 | 0.83 | SLC6A7 (0.59) | KDM4ESLC6A7RXFP1GPR119L3MBTL1 | |
| SCHEMBL1779865 | 0.83 | KDM4E (0.52) | KDM4ESLC6A7RXFP1GPR119 | |
| SCHEMBL3710705 | 0.82 | SLC6A7 (0.62) | KDM4ESLC6A7RXFP1GPR119L3MBTL1 | |
| SCHEMBL13073553 | 0.81 | SLC6A7 (0.57) | KDM4ESLC6A7RXFP1GPR119CKS1B | |
| SCHEMBL14224744 | 0.80 | CKS1B (0.53) | KDM4ESLC6A7RXFP1GPR119CKS1B | |
| SCHEMBL1439167 | 0.79 | KDM4E (0.69) | KDM4ERXFP1GPR119TP53L3MBTL1 | |
| SCHEMBL18395354 | 0.78 | KDM4E (0.68) | KDM4ERXFP1GPR119TP53L3MBTL1 | |
| SCHEMBL12639920 | 0.78 | KDM4E (0.72) | KDM4ERXFP1GPR119TP53L3MBTL1 | |
| SCHEMBL14411664 | 0.78 | SLC6A7 (0.54) | KDM4ESLC6A7GPR119 | |
| SCHEMBL22481434 | 0.77 | SLC6A7 (0.53) | KDM4ESLC6A7GPR119CKS1BSKP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4439606-A | ANTICHOLESTEROL, ANTILIPEMIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1984-03-27 | — | — | US | claimed |