Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.50 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.46 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.45 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24483184 | 0.89 | KMT2A (0.62) | POLBHTTMEN1KMT2AHSD17B10 | |
| SCHEMBL11433418 | 0.84 | HSD17B10 (0.67) | POLBHSD17B10MTNR1AMTNR1B | |
| SCHEMBL14430371 | 0.83 | POLB (0.61) | POLBHSD17B10PDE4BMTNR1AMTNR1B | |
| SCHEMBL9812423 | 0.83 | POLB (0.57) | POLBHTTMEN1KMT2AHSD17B10 | |
| SCHEMBL23386065 | 0.83 | POLB (0.65) | POLBHTTHSD17B10PDE4BMTNR1A | |
| SCHEMBL27788117 | 0.83 | POLB (0.60) | POLBMEN1KMT2AHSD17B10PDE4B | |
| SCHEMBL14255243 | 0.82 | MEN1 (0.47) | POLBHTTMEN1KMT2AMTNR1A | |
| SCHEMBL26679226 | 0.81 | POLB (0.59) | POLBHTTMEN1KMT2AHSD17B10 | |
| SCHEMBL25648716 | 0.81 | POLB (0.71) | POLBHTTMEN1KMT2AHSD17B10 | |
| SCHEMBL11080242 | 0.81 | POLB (0.55) | POLBHTTMEN1KMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4473586-A | Aminoalkyl dihydronaphthalenes | ABBOTT LABORATORIES (US) | 1984-09-25 | — | — | US | disclosed |