SCHEMBL11080253

SCHEMBL11080253

C[N+](C)(C)CCOC(=O)c1c2ccccc2cc2ccccc12

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.48
ALDH1A1 P00352 5/20 0.48
HPGD P15428 5/20 0.48
MEN1 O00255 4/20 0.48
KMT2A Q03164 4/20 0.48
L3MBTL1 Q9Y468 2/20 0.48
CHRM2 P08172 2/20 0.48
CHRM4 P08173 2/20 0.48
CHRM1 P11229 2/20 0.48
CHRM3 P20309 2/20 0.48
GLA P06280 2/20 0.46
CYP1A2 P05177 2/20 0.46
HSD17B10 Q99714 2/20 0.46
CYP2C19 P33261 1/20 0.46
ACHE P22303 2/20 0.46
BCHE P06276 1/20 0.46
LMNA P02545 3/20 0.45
MAPT P10636 3/20 0.45
MAPK1 P28482 3/20 0.45
TDP1 Q9NUW8 3/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17323599 0.91 KDM4E (0.46) KDM4EALDH1A1HPGDMEN1KMT2A
SCHEMBL17323589 0.87 ALDH1A1 (0.45) KDM4EALDH1A1HPGDMEN1KMT2A
SCHEMBL16352946 0.85 CHRM2 (0.49) KDM4EALDH1A1HPGDMEN1KMT2A
SCHEMBL17323598 0.84 KDM4E (0.48) KDM4EALDH1A1HPGDMEN1KMT2A
SCHEMBL17323607 0.84 ALDH1A1 (0.43) KDM4EALDH1A1HPGDMEN1KMT2A
SCHEMBL6880564 0.83 ALDH1A1 (0.56) KDM4EALDH1A1HPGDMEN1KMT2A
SCHEMBL16352984 0.82 ALDH1A1 (0.43) KDM4EALDH1A1HPGDMEN1KMT2A
SCHEMBL17323595 0.82 KDM4E (0.48) KDM4EALDH1A1HPGDMEN1KMT2A
SCHEMBL14440745 0.81 KDM4E (0.50) KDM4EALDH1A1HPGDMEN1KMT2A
SCHEMBL17323600 0.81 TSHR (0.46) KDM4EALDH1A1HPGDMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4470995-A Use of 9-anthroylcholine as a vaginal contraceptive UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 1984-09-11 US claimed
EP-0102162-A1 Use of calmodulin binding drugs for preventing pregnancy THE UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 1984-03-07 EP claimed
WO-1984000297-A1 USE OF CALMODULIN BINDING DRUGS AS VAGINAL CONTRACEPTIVES UNIV GEORGIA RES FOUND (US) 1984-02-02 WO claimed
US-4421764-A Use of 9-anthroylcholine in the uterus to prevent pregnancy UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 1983-12-20 US claimed
EP-0082203-A1 USE OF CALMODULIN BINDING DRUGS IN UTERUS TO PREVENT PREGNANCY THE UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 1983-06-29 EP claimed
WO-1983000086-A1 USE OF CALMODULIN BINDING DRUGS IN UTERUS TO PREVENT PREGNANCY UNIV GEORGIA RES FOUND (US) 1983-01-20 WO claimed
US-20250241928-A1 CALMODULIN INHIBITORS FOR THE TREATMENT OF RIBOSOMAL DISORDERS AND RIBOSOMOPATHIES CHILDREN'S MEDICAL CENTER CORPORATION (US) 2025-07-31 US disclosed
US-12280064-B2 Calmodulin inhibitors for the treatment of ribosomal disorders and ribosomopathies CHILDREN'S MEDICAL CENTER CORPORATION 2025-04-22 US disclosed
US-20240215891-A1 Bio-Electrode Composition, Bio-Electrode, And Method For Manufacturing Bio-Electrode SHIN-ETSU CHEMICAL CO., LTD. (JP) 2024-07-04 US disclosed
US-20240215890-A1 Bio-Electrode, Bio-Electrode Composition, And Method For Manufacturing Bio-Electrode SHIN-ETSU CHEMICAL CO., LTD. (JP) 2024-07-04 US disclosed
US-20240091238-A1 CALMODULIN INHIBITORS FOR THE TREATMENT OF RIBOSOMAL DISORDERS AND RIBOSOMOPATHIES CHILDREN'S MEDICAL CENTER CORPORATION (US) 2024-03-21 US disclosed
EP-4306558-A1 BIOELECTRODE, PRODUCTION METHOD FOR BIOELECTRODE, AND MEASUREMENT METHOD FOR BIOSIGNALS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2024-01-17 EP disclosed
US-11839700-B2 Bio-electrode composition, bio-electrode, and method for manufacturing a bio-electrode SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-12-12 US disclosed
US-4421764-A Use of 9-anthroylcholine in the uterus to prevent pregnancy UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 1983-12-20 US disclosed
US-4421764-A Use of 9-anthroylcholine in the uterus to prevent pregnancy UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 1983-12-20 US disclosed
US-4421764-A Use of 9-anthroylcholine in the uterus to prevent pregnancy UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 1983-12-20 US disclosed
US-4419366-A Use of N-(6 aminohexyl)-5-chloro-1-naphthalenesulfonamide, N-(6 aminohexyl)-5-chloro-2-naphthalenesulfonamide, or N-(6 aminohexyl)-5-bromo-2-naphthalenesulfonamide in the uterus to prevent pregnancy UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 1983-12-06 US disclosed
US-4416900-A Use of N-phenyl-1-naphthylamine in the uterus to prevent pregnancy UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 1983-11-22 US disclosed
US-4416897-A Use of 8-anilino-1-naphthalenesulfonate in the uterus to prevent pregnancy UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 1983-11-22 US disclosed
US-4377577-A Use of psychoactive drugs in uterus to prevent pregnancy UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 1983-03-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240091238-A1 CALMODULIN INHIBITORS FOR THE TREATMENT OF RIBOSOMAL DISORDERS AND RIBOSOMOPATHIES CALM1, RACK1, CAMK2B KDM4E 1675/4885ALDH1A1 3729/4885HPGD 3781/4885
US-20250241928-A1 CALMODULIN INHIBITORS FOR THE TREATMENT OF RIBOSOMAL DISORDERS AND RIBOSOMOPATHIES CALM1, RACK1, CAMK2B KDM4E 1675/4885ALDH1A1 3729/4885HPGD 3781/4885
US-12280064-B2 Calmodulin inhibitors for the treatment of ribosomal disorders and ribosomopathies CALM1, RACK1, CAMK2B KDM4E 1675/4885ALDH1A1 3729/4885HPGD 3781/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.