Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | FOLH1 | Q04609 | 6/20 | 0.33 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.33 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.32 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL726981 | 0.85 | TP53 (0.40) | TDP1SMN1; SMN2PRSS1TMPRSS15MMP1 | |
| SCHEMBL18219430 | 0.85 | TDP1 (0.41) | TDP1MMP1MMP2MMP3MMP9 | |
| SCHEMBL2180353 | 0.83 | TP53 (0.39) | TDP1SMN1; SMN2PRSS1TMPRSS15MMP1 | |
| SCHEMBL11856851 | 0.83 | TP53 (0.39) | TDP1SMN1; SMN2PRSS1TMPRSS15MMP1 | |
| SCHEMBL9245267 | 0.83 | TDP1 (0.37) | TDP1SMN1; SMN2PRSS1TMPRSS15ALOX15 | |
| SCHEMBL11855836 | 0.82 | TP53 (0.37) | TDP1SMN1; SMN2PRSS1TMPRSS15MMP1 | |
| SCHEMBL2550509 | 0.80 | LAP3 (0.37) | SMN1; SMN2PRSS1TMPRSS15SLC22A6CACNA2D1 | |
| SCHEMBL7456354 | 0.80 | SMN1; SMN2 (0.38) | TDP1SMN1; SMN2MMP1MMP2MMP3 | |
| SCHEMBL24430 | 0.78 | SMN1; SMN2 (0.52) | TDP1SMN1; SMN2PRSS1TMPRSS15ALOX15 | |
| SCHEMBL1179759 | 0.78 | SMN1; SMN2 (0.52) | TDP1SMN1; SMN2PRSS1TMPRSS15ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4460782-A | FUNGICIDES | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) | 1984-07-17 | — | — | US | disclosed |