SCHEMBL24430

SCHEMBL24430

O=C(O)CC(O)C(=O)OC(CC(=O)O)C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.52
SLC22A6 Q4U2R8 1/20 0.39
TDP1 Q9NUW8 1/20 0.37
TET2 Q6N021 6/20 0.33
GABRR1 P24046 2/20 0.33
KDM4A O75164 2/20 0.33
KDM4C Q9H3R0 2/20 0.33
KDM2A Q9Y2K7 2/20 0.33
TET3 O43151 2/20 0.33
LMNA P02545 1/20 0.33
OR51E2 Q9H255 1/20 0.32
TET1 Q8NFU7 1/20 0.31
FOLH1 Q04609 1/20 0.31
PRSS1 P07477 1/20 0.31
TMPRSS15 P98073 1/20 0.31
ALOX15 P16050 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1179759 1.00 SMN1; SMN2 (0.52) SMN1; SMN2SLC22A6TDP1TET2GABRR1
Ammonia Solution, Strong SCHEMBL2586848 0.98 SMN1; SMN2 (0.50) SMN1; SMN2SLC22A6TDP1TET2GABRR1
Malic Acid SCHEMBL14125843 0.96 SMN1; SMN2 (0.60) SMN1; SMN2SLC22A6TDP1TET2GABRR1
SCHEMBL29144651 0.90 SMN1; SMN2 (0.41) SMN1; SMN2SLC22A6TDP1TET2GABRR1
SCHEMBL25255556 0.81 SMN1; SMN2 (0.39) SMN1; SMN2SLC22A6TDP1GABRR1LMNA
SCHEMBL726981 0.81 TP53 (0.40) SMN1; SMN2SLC22A6TDP1FOLH1PRSS1
SCHEMBL3386666 0.81 TSHR (0.42) SMN1; SMN2SLC22A6TDP1GABRR1LMNA
SCHEMBL157637 0.80 SMN1; SMN2 (0.54) SMN1; SMN2SLC22A6TDP1TET2GABRR1
SCHEMBL2180353 0.79 TP53 (0.39) SMN1; SMN2SLC22A6TDP1FOLH1PRSS1
SCHEMBL11856851 0.79 TP53 (0.39) SMN1; SMN2SLC22A6TDP1FOLH1PRSS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8597419-B2 Preservative compositions for wood and like materials GENICS INC. (CA) 2013-12-03 US claimed
EP-2401227-A2 REACTION TUBE AND HYDROTHERMAL PROCESSING FOR THE WET CHEMICAL CO-PRECIPITATION OF OXIDE POWDERS Eestor, Inc. (US) 2012-01-04 EP claimed
WO-2011133436-A1 COATINGS FOR IMPLANTABLE DEVICES COMPRISING POLYMERS OF LACTIC ACID AND METHODS FOR FABRICATING THE SAME ABBOTT CARDIOVASCULAR SYSTEMS INC. (US) 2011-10-27 WO claimed
US-20110053758-A1 REACTION TUBE AND HYDROTHERMAL PROCESSING FOR THE WET CHEMICAL CO-PRECIPITATION OF OXIDE POWDERS EESTOR, INC. (US) 2011-03-03 US claimed
US-20110027336-A1 COATINGS FOR IMPLANTABLE DEVICES COMPRISING POLYMERS OF LACTIC ACID AND METHODS FOR FABRICATING THE SAME ADVANCED CARDIOVASCULAR SYSTEMS, INC. (US) 2011-02-03 US claimed
US-20100062166-A1 PRESERVATIVE COMPOSITIONS FOR WOOD AND LIKE MATERIALS GENICS INC. (CA) 2010-03-11 US claimed
US-5310832-A Agitation SHIN-ETSU CHEMICAL CO., LTD. (JP) 1994-05-10 US claimed
CN-117679329-B Sun-proof synergistic composition and application thereof 广州玥颜化妆品有限公司 2024-05-24 CN disclosed
WO-2024058984-A2 METHODS AND USES OF MICROBIOME COMPOSITIONS, COMPONENTS, OR METABOLITES FOR TREATING INSULIN-ASSOCIATED DISEASES MarvelBiome, Inc. (US) 2024-03-21 WO disclosed
CN-117679329-A Sun-proof synergistic composition and application thereof 广州玥颜化妆品有限公司 2024-03-12 CN disclosed
CN-112137912-B Application of dextrin palmitate as sun-screening synergist in sun-screening cosmetics 养生堂(安吉)化妆品有限公司 2023-06-20 CN disclosed
US-11602502-B2 Three-dimensional (3D) printing a pharmaceutical tablet HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2023-03-14 US disclosed
US-20190343769-A1 THREE-DIMENSIONAL (3D) PRINTING A PHARMACEUTICAL TABLET HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2019-11-14 US disclosed
EP-1702056-A2 NON-ANIMAL PRODUCT CONTAINING VETERINARY FORMULATIONS Merial Limited (US) 2006-09-20 EP disclosed
WO-2005062782-A2 NON-ANIMAL PRODUCT CONTAINING VETERINARY FORMULATIONS MERIAL LIMITED (US) 2005-07-14 WO disclosed
EP-0401215-A4 HYDROPHILIC CARBOXY POLYURETHANES 1991-01-09 EP disclosed
EP-0401215-A1 HYDROPHILIC CARBOXY POLYURETHANES TYNDALE PLAINS-HUNTER, LTD. (US) 1990-12-12 EP disclosed
WO-1989007619-A1 HYDROPHILIC CARBOXY POLYURETHANES TYNDALE PLAINS-HUNTER, LTD. (US) 1989-08-24 WO disclosed
US-4629690-A COMPETITIVE PROTEIN BINDING USING A SECOND ENZYME RELATED TO THE FIRST BY THE PRODUCT OF ONE BEING THE SUBSTRATE OF THE OTHER SYNTEX (U.S.A.) INC. (US) 1986-12-16 US disclosed
US-4483942-A CITRIC OR MALIC ACID AS STABILIZER NIPPON OIL CO., LTD. (JP) 1984-11-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110027336-A1 COATINGS FOR IMPLANTABLE DEVICES COMPRISING POLYMERS OF LACTIC ACID AND METHODS FOR FABRICATING THE SAME LDHA, LDHB, CA1 SMN1; SMN2 3049/4885SLC22A6 826/4885TDP1 3088/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.