Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 9/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11086256 | 0.89 | ADORA3 (0.49) | ADORA3ELANEKDM4EALDH1A1LMNA | |
| SCHEMBL11082599 | 0.85 | ADORA3 (0.48) | ADORA3ADORA2A | |
| Melquinast SCHEMBL2109337 | 0.83 | ADORA3 (0.56) | ADORA3ELANEKDM4EALDH1A1TSHR | |
| SCHEMBL11077725 | 0.82 | ADORA3 (0.40) | ADORA3ELANEKDM4EALDH1A1LMNA | |
| SCHEMBL11085127 | 0.78 | ADORA3 (0.60) | ADORA3ELANEKDM4EALDH1A1TSHR | |
| SCHEMBL11086548 | 0.78 | ADORA3 (0.49) | ADORA3KDM4EALDH1A1MAPT | |
| SCHEMBL11088377 | 0.77 | ADORA3 (0.49) | ADORA3ADORA2A | |
| SCHEMBL11172028 | 0.73 | CTSL (0.40) | ELANEKDM4EALDH1A1LMNATSHR | |
| SCHEMBL11087008 | 0.73 | ADORA3 (0.57) | ADORA3ELANELMNAADORA2A | |
| SCHEMBL11089403 | 0.73 | ADORA3 (0.55) | ADORA3ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4463007-A | ANTIALLERGENS | BASF AKTIENGESELLSCHAFT (DE) | 1984-07-31 | — | — | US | disclosed |