Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.65 |
| ▸ | HPGD | P15428 | 3/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.65 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | GRM5 | P41594 | 1/20 | 0.51 |
| ▸ | FBP1 | P09467 | 1/20 | 0.47 |
| ▸ | DHFR | P00374 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | RHEB | Q15382 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2282611 | 0.80 | POLB (0.56) | ALDH1A1KDM4EKMT2AHPGDMEN1 | |
| SCHEMBL30688805 | 0.80 | POLB (0.56) | ALDH1A1KDM4EKMT2AHPGDMEN1 | |
| SCHEMBL29543630 | 0.80 | POLB (0.56) | ALDH1A1KDM4EKMT2AHPGDMEN1 | |
| SCHEMBL10596007 | 0.78 | POLB (0.55) | ALDH1A1KDM4EKMT2AHPGDMEN1 | |
| SCHEMBL190886 | 0.77 | ALDH1A1 (0.53) | ALDH1A1KDM4EKMT2AHPGDMEN1 | |
| SCHEMBL10394650 | 0.77 | L3MBTL1 (0.62) | ALDH1A1KDM4EKMT2AHPGDMEN1 | |
| SCHEMBL9377350 | 0.77 | KDM4E (0.49) | ALDH1A1KDM4EKMT2AHPGDMEN1 | |
| SCHEMBL10708413 | 0.76 | POLB (0.62) | ALDH1A1KDM4EKMT2AHPGDMEN1 | |
| SCHEMBL6136932 | 0.75 | ALDH1A1 (0.68) | ALDH1A1KDM4EKMT2AHPGDMEN1 | |
| SCHEMBL3282084 | 0.74 | POLB (0.56) | ALDH1A1KDM4EKMT2AHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4427437-A | PLANT GROWTH REGULATORS | ICI AUSTRALIA LIMITED (AU) | 1984-01-24 | — | — | US | disclosed |
| EP-0001187-A1 | 2-phenoxy-pyrimidines and their use as pesticides | ICI AUSTRALIA LIMITED (AU) | 1979-03-21 | — | — | EP | disclosed |