SCHEMBL11080682

SCHEMBL11080682

CC(=O)C1(CO)CC2CCC1C2

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 1/20 0.34
ALOX5AP P20292 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11076216 0.89
SCHEMBL12424267 0.85 HSD11B1 (0.34) HSD11B1
SCHEMBL13344441 0.82 HSD11B1 (0.33) HSD11B1
SCHEMBL5930739 0.74 HSD11B1 (0.37) HSD11B1
SCHEMBL11258826 0.73 ALDH1A1 (0.54)
SCHEMBL11081234 0.73 EPHX1 (0.36) HSD11B1
SCHEMBL24240563 0.73 HSD11B1 (0.36) HSD11B1
SCHEMBL32688629 0.73 HSD11B1 (0.37) HSD11B1
SCHEMBL11076819 0.72 ALDH1A1 (0.34)
SCHEMBL32688805 0.71 HSD11B1 (0.35) HSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0026369-B1 CARBAMATES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM BASF Aktiengesellschaft (DE) 1984-08-08 EP disclosed
US-4335138-A HYPNOTIC, SEDATIVE BASF AKTIENGESELLSCHAFT (DE) 1982-06-15 US disclosed
EP-0026369-A2 Carbamates, their preparation and pharmaceutical compositions containing them BASF Aktiengesellschaft (DE) 1981-04-08 EP disclosed