SCHEMBL1108079

SCHEMBL1108079

CCCC(=O)NCCOc1ccc(C)cc1

nearest known ligand 0.67

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.67
NPC1 O15118 3/20 0.63
HPGD P15428 2/20 0.56
HTT P42858 1/20 0.56
HDAC1 Q13547 1/20 0.55
MEN1 O00255 3/20 0.55
POLB P06746 1/20 0.55
L3MBTL1 Q9Y468 1/20 0.54
ALDH1A1 P00352 2/20 0.53
TP53 P04637 1/20 0.53
MAPK1 P28482 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
HSD17B10 Q99714 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4634361 0.86 RECQL (0.69) KMT2ANPC1HPGDMEN1L3MBTL1
SCHEMBL10389706 0.84 NPC1 (0.67) KMT2ANPC1HPGDHDAC1MEN1
SCHEMBL10050488 0.83 RECQL (0.74) KMT2ANPC1HPGDHTTHDAC1
SCHEMBL21595955 0.82 NPC1 (0.73) KMT2ANPC1HPGDMEN1POLB
SCHEMBL171846 0.80 MTNR1A (0.75) KMT2ANPC1HPGDMEN1POLB
SCHEMBL11886540 0.79 NPC1 (0.65) KMT2ANPC1HPGDMEN1POLB
SCHEMBL10191978 0.79 NPC1 (0.65) KMT2ANPC1HPGDMEN1POLB
Hydrochloric Acid SCHEMBL30832634 0.79 MTNR1A (0.73) KMT2ANPC1HPGDMEN1POLB
SCHEMBL807668 0.79 NPC1 (0.69) KMT2ANPC1HPGDMEN1POLB
SCHEMBL12223549 0.78 L3MBTL1 (0.62) KMT2ANPC1HPGDHTTHDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8524116-B2 Multilayer sheet containing optically anisotropic layer containing liquid crystal compound and cellulose ester with polymer FUJIFILM CORPORATION (JP) 2013-09-03 US disclosed
US-8524116-B2 Multilayer sheet containing optically anisotropic layer containing liquid crystal compound and cellulose ester with polymer FUJIFILM CORPORATION (JP) 2013-09-03 US disclosed
US-8153246-B2 Optical compensatory film, polarizing plate, and liquid crystal display device FUJIFILM CORPORATION (JP) 2012-04-10 US disclosed
US-7876403-B2 Optical compensation film, polarizing plate and liquid crystal display device FUJIFILM CORPORATION (JP) 2011-01-25 US disclosed
US-7872716-B2 Optical compensation film, polarizing plate and liquid crystal display FUJIFILM CORPORATION (JP) 2011-01-18 US disclosed
US-7799242-B2 Liquid crystalline composition, optically anisotropic film, optical film, and polarizer and liquid-crystal display device using them FUJIFILM CORPORATION (JP) 2010-09-21 US disclosed
US-20090273740-A1 OPTICAL COMPENSATORY FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2009-11-05 US disclosed
US-20090180059-A1 OPTICAL COMPENSATION FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2009-07-16 US disclosed
US-20090040435-A1 LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2009-02-12 US disclosed
US-20080225210-A1 Optical Compensation Film, Polarizing Plate, and Liquid Crystal Display Device FUJIFILM CORPORATION (JP) 2008-09-18 US disclosed
US-20080203357-A1 Liquid Crystalline Composition, Optically Anisotropic Film, Optical Film, and Polarizer and Liquid-Crystal Display Device Using Them FUJIFILM CORPORATION (JP) 2008-08-28 US disclosed
US-20080199637-A1 Optical Compensatory Film, Process for Producing the Same, and Polarizing Plate and Liquid Crystal Display Employing the Same FUJIFILM CORPORATION (JP) 2008-08-21 US disclosed
US-20080192191-A1 Optical Compensation Film, Polarizing Plate and Liquid Crystal Display FUJIFILM CORPORATION (JP) 2008-08-14 US disclosed
US-7311949-B2 Composition, optical film, polarizing plate and liquid crystal display FUJIFILM CORPORATION (JP) 2007-12-25 US disclosed
US-7311950-B2 Composition, optical compensatory film and liquid crystal display FUJIFILM CORPORATION (JP) 2007-12-25 US disclosed