Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 6/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.51 |
| ▸ | TUBB | P07437 | 2/20 | 0.51 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.51 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.51 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.51 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.51 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.51 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.51 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.51 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.51 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.51 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.51 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11080917 | 1.00 | RAB9A (0.59) | RAB9ANPC1ALOX5MEN1KMT2A | |
| SCHEMBL11088808 | 0.89 | RAB9A (0.56) | RAB9ANPC1ALOX5MEN1KMT2A | |
| SCHEMBL11088813 | 0.89 | RAB9A (0.56) | RAB9ANPC1ALOX5MEN1KMT2A | |
| SCHEMBL11087084 | 0.89 | RAB9A (0.61) | RAB9ANPC1ALOX5MEN1KMT2A | |
| SCHEMBL11086751 | 0.89 | RAB9A (0.61) | RAB9ANPC1ALOX5MEN1KMT2A | |
| SCHEMBL11081588 | 0.88 | RAB9A (0.57) | RAB9ANPC1ALOX5MEN1KMT2A | |
| SCHEMBL11090834 | 0.88 | RAB9A (0.78) | RAB9ANPC1ALOX5MEN1KMT2A | |
| SCHEMBL11090836 | 0.88 | RAB9A (0.78) | RAB9ANPC1ALOX5MEN1KMT2A | |
| SCHEMBL11081584 | 0.88 | RAB9A (0.57) | RAB9ANPC1ALOX5MEN1KMT2A | |
| SCHEMBL11090611 | 0.86 | RAB9A (0.56) | RAB9ANPC1ALOX5MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4428952-A | Substituted pyrrolo[2,1-b]quinazolines and pyrido[2,1-b]quinazolines useful for the treatment of or the prevention of gastrointestinal ulcers | FARMITALIA CARLO ERBA S.P.A. (IT) | 1984-01-31 | — | — | US | disclosed |