SCHEMBL1108093

SCHEMBL1108093

CCCCCCCCCCOCCOc1ccc(S(=O)(=O)O)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.54
CA12 O43570 1/20 0.54
CA1 P00915 1/20 0.54
CA2 P00918 1/20 0.54
CA7 P43166 1/20 0.54
CA9 Q16790 1/20 0.54
NR5A1 Q13285 1/20 0.53
RARB P10826 4/20 0.52
MAPK1 P28482 2/20 0.52
MEN1 O00255 1/20 0.52
USP2 O75604 1/20 0.52
ALDH1A1 P00352 1/20 0.52
LMNA P02545 1/20 0.52
CYP3A4 P08684 1/20 0.52
CASP1 P29466 1/20 0.52
KMT2A Q03164 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
SLCO1B3 Q9NPD5 1/20 0.52
SLCO1B1 Q9Y6L6 1/20 0.52
TP53 P04637 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1108100 1.00 TSHR (0.54) TSHRCA12CA1CA2CA7
SCHEMBL4524560 0.92 TSHR (0.62) TSHRCA12CA1CA2CA7
SCHEMBL4529708 0.92 TSHR (0.62) TSHRCA12CA1CA2CA7
SCHEMBL4532493 0.92 TSHR (0.62) TSHRCA12CA1CA2CA7
SCHEMBL4537643 0.92 TSHR (0.62) TSHRCA12CA1CA2CA7
SCHEMBL4533781 0.92 TSHR (0.62) TSHRCA12CA1CA2CA7
SCHEMBL4533770 0.92 TSHR (0.62) TSHRCA12CA1CA2CA7
SCHEMBL4527703 0.92 TSHR (0.62) TSHRCA12CA1CA2CA7
SCHEMBL4530059 0.92 TSHR (0.62) TSHRCA12CA1CA2CA7
SCHEMBL4539506 0.92 TSHR (0.62) TSHRCA12CA1CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8153246-B2 Optical compensatory film, polarizing plate, and liquid crystal display device FUJIFILM CORPORATION (JP) 2012-04-10 US disclosed
US-20090273740-A1 OPTICAL COMPENSATORY FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2009-11-05 US disclosed