Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | PREP | P48147 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | NMT2 | O60551 | 1/20 | 0.44 |
| ▸ | NMT1 | P30419 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ERN1 | O75460 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TACR1 | P25103 | 1/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11056730 | 0.75 | PDE10A (0.67) | KDM4EMEN1KMT2ATP53HSD17B10 | |
| Ethyl Acetate SCHEMBL11084099 | 0.74 | KDM4E (0.52) | KDM4EL3MBTL1NMT2NMT1MEN1 | |
| SCHEMBL538291 | 0.73 | SMN1; SMN2 (0.69) | KDM4ENMT2NMT1MEN1KMT2A | |
| Acetonitrile SCHEMBL11086316 | 0.70 | MEN1 (0.53) | L3MBTL1MEN1KMT2ATP53SMN1; SMN2 | |
| SCHEMBL11083265 | 0.70 | ADORA3 (0.63) | KDM4EMEN1KMT2ATP53SMN1; SMN2 | |
| SCHEMBL34468785 | 0.69 | KDM4E (0.46) | KDM4EPREPL3MBTL1MEN1KMT2A | |
| SCHEMBL28304019 | 0.69 | KMT2A (0.55) | KDM4ENMT2NMT1MEN1KMT2A | |
| SCHEMBL3087861 | 0.68 | ADORA3 (0.65) | L3MBTL1HSD17B10HTTHPGDRAB9A | |
| SCHEMBL12903055 | 0.68 | MEN1 (0.73) | KDM4EL3MBTL1MEN1KMT2AHTT | |
| SCHEMBL10969061 | 0.68 | MAPT (0.55) | KDM4EMEN1KMT2ATP53HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4450167-A | TRANQUILIZERS; PSYCHOLOGICAL DISORDERS | ROUSSEL UCLAF (FR) | 1984-05-22 | — | — | US | disclosed |