Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NMT2 | O60551 | 1/20 | 0.44 |
| ▸ | NMT1 | P30419 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TOP2A | P11388 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11075264 | 0.80 | KDM4E (0.61) | KDM4EALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL15782876 | 0.77 | KDM4E (0.49) | KDM4EL3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL4992903 | 0.76 | FABP3 (0.52) | KDM4EL3MBTL1ALDH1A1MEN1KMT2A | |
| Acetonitrile SCHEMBL11081574 | 0.74 | KDM4E (0.47) | KDM4EL3MBTL1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL29860485 | 0.70 | SMN1; SMN2 (0.58) | KDM4EALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL27659536 | 0.70 | SMN1; SMN2 (0.58) | KDM4EALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL538291 | 0.70 | SMN1; SMN2 (0.69) | KDM4EALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL4471456 | 0.69 | FABP3 (0.55) | KDM4EL3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL19002791 | 0.69 | ALDH1A1 (0.66) | KDM4EL3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL15503685 | 0.69 | KDM4E (1.00) | KDM4EL3MBTL1ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4450167-A | TRANQUILIZERS; PSYCHOLOGICAL DISORDERS | ROUSSEL UCLAF (FR) | 1984-05-22 | — | — | US | disclosed |