Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 12/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.68 |
| ▸ | PGR | P06401 | 6/20 | 0.68 |
| ▸ | LMNA | P02545 | 3/20 | 0.68 |
| ▸ | AR | P10275 | 2/20 | 0.68 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.68 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.68 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.68 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.68 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.68 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.68 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.68 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.68 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.62 |
| ▸ | CNR1 | P21554 | 1/20 | 0.62 |
| ▸ | USP2 | O75604 | 3/20 | 0.61 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | MLNR | O43193 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4003694 | 0.93 | NR3C1 (0.68) | NR3C1CYP3A4PGRLMNAAR | |
| SCHEMBL4224907 | 0.93 | NR3C1 (0.68) | NR3C1CYP3A4PGRLMNAAR | |
| SCHEMBL4003695 | 0.92 | NR3C1 (0.67) | NR3C1CYP3A4PGRLMNAAR | |
| SCHEMBL4224909 | 0.92 | NR3C1 (0.67) | NR3C1CYP3A4PGRLMNAAR | |
| SCHEMBL4102916 | 0.92 | NR3C1 (0.72) | NR3C1CYP3A4PGRLMNAAR | |
| SCHEMBL11251406 | 0.92 | NR3C1 (0.72) | NR3C1CYP3A4PGRLMNAAR | |
| SCHEMBL11037864 | 0.92 | NR3C1 (0.72) | NR3C1CYP3A4PGRLMNAAR | |
| SCHEMBL4216341 | 0.92 | NR3C1 (0.66) | NR3C1CYP3A4PGRLMNAAR | |
| SCHEMBL11037205 | 0.91 | NR3C1 (0.83) | NR3C1CYP3A4PGRLMNAAR | |
| Dexamethasone Acefurate SCHEMBL139744 | 0.91 | NR3C1 (0.69) | NR3C1CYP3A4PGRLMNAAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4472393-A | ANTIINFLAMMATORY AGENTS | SCHERING CORPORATION (US) | 1984-09-18 | — | — | US | disclosed |
| EP-0057401-A1 | Aromatic heterocyclic esters of steroids, their preparation and pharmaceutical compositions containing them | SCHERING CORPORATION (US) | 1982-08-11 | — | — | EP | disclosed |